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Comparison of different oval window sealing materials in stapes surgery: systematic review and meta-analysis.
Scarpa, Alfonso; Marra, Pasquale; Ralli, Massimo; Viola, Pasquale; Gioacchini, Federico Maria; Chiarella, Giuseppe; Salzano, Francesco Antonio; De Luca, Pietro; Ricciardiello, Filippo; Cassandro, Claudia; Corbi, Grazia Maria.
Afiliación
  • Scarpa A; Department of Medicine, Surgery and Dentistry, University of Salerno, Largo Città di Ippocrate, 84131, Salerno, Italy. ascarpa@unisa.it.
  • Marra P; Department of Medicine, Surgery and Dentistry, University of Salerno, Largo Città di Ippocrate, 84131, Salerno, Italy.
  • Ralli M; Department of Sense Organs, Sapienza University of Rome, Rome, Italy.
  • Viola P; Department of Experimental and Clinical Medicine, Unit of Audiology, Regional Centre for Cochlear Implants and ENT Diseases, Magna Graecia University, Catanzaro, Italy.
  • Gioacchini FM; ENT Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy.
  • Chiarella G; Department of Experimental and Clinical Medicine, Unit of Audiology, Regional Centre for Cochlear Implants and ENT Diseases, Magna Graecia University, Catanzaro, Italy.
  • Salzano FA; Department of Medicine, Surgery and Dentistry, University of Salerno, Largo Città di Ippocrate, 84131, Salerno, Italy.
  • De Luca P; Department of Medicine, Surgery and Dentistry, University of Salerno, Largo Città di Ippocrate, 84131, Salerno, Italy.
  • Ricciardiello F; Ear, Nose, and Throat Unit, AORN "Antonio Cardarelli", 80131, Naples, Italy.
  • Cassandro C; Department of Surgical Sciences, University of Turin, Turin, Italy.
  • Corbi GM; Department Medicine and Health Sciences, University of Molise, Campobasso, Italy.
Eur Arch Otorhinolaryngol ; 279(12): 5521-5533, 2022 Dec.
Article en En | MEDLINE | ID: mdl-35857099
OBJECTIVE: To compare the efficacy and safety characteristics of different materials used for oval window sealing during stapedotomy. METHODS: A systematic review was conducted according to the PRISMA guidelines. Published international English literature from January 1, 2000 to December 2021 was screened, checking for studies that compared different materials utilization in patients undergoing stapedotomy surgery for otosclerosis or congenital stapes fixation. Data related to the efficacy and safety of each material were extracted. The primary outcome measure was the air-bone gap (ABG) closure after surgical intervention. RESULTS: Six studies were included in the metanalysis. Because of the heterogeneity of the treatments adopted, we assessed the use of the fat compared to all other treatments, and the use of the gelfoam compared to all other treatments. In the former analysis (fat vs others) we did not identify differences in ABG closure between the groups (p = 0.74), with a low heterogeneity of the results (I2 = 28.36%; Hedge's g = 0.04, 95% CI - 0.19 0.27); similarly, we did not identify differences between the use of gelfoam and other treatments (p = 0.97), with a low heterogeneity of the results (I2 = 28.91%; Hedge's g = 0.00, 95% CI - 0.20 0.21). CONCLUSIONS: Numerous options are available for oval window sealing during stapedotomy, with acceptable safety and effectiveness profiles. Based on the current data, no definitive recommendation can be made regarding the choice of one material over another, and the convenience of sealing over no sealing at all.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Otosclerosis / Cirugía del Estribo Tipo de estudio: Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Eur Arch Otorhinolaryngol Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Otosclerosis / Cirugía del Estribo Tipo de estudio: Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Eur Arch Otorhinolaryngol Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Alemania