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Complete Response of High Microsatellite Instability Gastric Cancer and Synchronous Microsatellite Stability Rectal Cancer.
Hunzeker, Zachary E; Bhakta, Pooja; Gudipally, Sindusha R; Kavuri, Sri Bharathi; Venkatesan, Rohit; Nwanze, Chukwuyejulumafor.
Afiliación
  • Hunzeker ZE; Medicine, University of Texas Medical Branch, Galveston, USA.
  • Bhakta P; Internal Medicine, University of Texas Medical Branch, Galveston, USA.
  • Gudipally SR; Oncology, University of Texas Medical Branch, Galveston, USA.
  • Kavuri SB; Pathology, University of Texas Medical Branch, Galveston, USA.
  • Venkatesan R; Oncology, University of Texas MD Anderson Cancer Center, Houston, USA.
  • Nwanze C; Pathology, University of Texas Medical Branch, Galveston, USA.
Cureus ; 14(6): e25820, 2022 Jun.
Article en En | MEDLINE | ID: mdl-35836435
Gastric cancer, a leading cause of cancer-related death in the world, may occur with an additional synchronous malignancy in rare cases. Of these rare cases many are colorectal cancer. Microsatellite instability is a phenomenon that may contribute to the pathogenesis of both cancers, as are field cancerization and genetic susceptibility, although none of these explain many concurrent cases. In this case, we described a patient with locally advanced microsatellite instability-high gastric cancer and synchronous microsatellite stable rectal cancer, who received a combination chemo-immunotherapy regimen and achieved complete response. This report reflects on current knowledge surrounding synchronous primary malignancies and achieving complete response.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos