Oxocrebanine from Stephania pierrei exerts macrophage anti-inflammatory effects by downregulating the NF-&#954;B, MAPK, and PI3K/Akt signalling pathways.

Chulrik, Wanatsanan; Jansakun, Chutima; Chaichompoo, Waraluck; Tedasen, Aman; Yotmanee, Pathumwadee; Sattayakhom, Apsorn; Chunglok, Wilanee; Suksamrarn, Apichart; Chunglok, Warangkana

Oxocrebanine from Stephania pierrei exerts macrophage anti-inflammatory effects by downregulating the NF-κB, MAPK, and PI3K/Akt signalling pathways.

Chulrik, Wanatsanan; Jansakun, Chutima; Chaichompoo, Waraluck; Tedasen, Aman; Yotmanee, Pathumwadee; Sattayakhom, Apsorn; Chunglok, Wilanee; Suksamrarn, Apichart; Chunglok, Warangkana.

Afiliación

Chulrik W; Health Sciences (International Program), College of Graduate Studies, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Jansakun C; School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Chaichompoo W; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
Tedasen A; School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Yotmanee P; Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, 10240, Thailand.
Sattayakhom A; School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Chunglok W; Division of Biological Science, Faculty of Science, Prince of Songkla University, Songkhla, 90110, Thailand.
Suksamrarn A; Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, 10240, Thailand.
Chunglok W; School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, 80160, Thailand. cwarang@wu.ac.th.

Inflammopharmacology ; 30(4): 1369-1382, 2022 Aug.

Article en En | MEDLINE | ID: mdl-35831735

Asunto(s)

Aporfinas; Stephania; Antiinflamatorios/metabolismo; Antiinflamatorios/farmacología; Aporfinas/metabolismo; Aporfinas/farmacología; Ciclooxigenasa 2/metabolismo; Lipopolisacáridos/farmacología; Macrófagos; Simulación del Acoplamiento Molecular; FN-kappa B/metabolismo; Óxido Nítrico/metabolismo; Óxido Nítrico Sintasa de Tipo II/metabolismo; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Stephania/metabolismo

Palabras clave

Aporphine alkaloid; Cyclooxygenase; Inflammatory pathway; Oxocrebanine; Stephania pierrei

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aporfinas / Stephania Idioma: En Revista: Inflammopharmacology Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2022 Tipo del documento: Article País de afiliación: Tailandia Pais de publicación: Suiza

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