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Pharmacogenetic testing in pediatric neurology: a pragmatic study evaluating clinician and patient perceptions.
Pépin, Marie-Anne; Otis, Anne-Sophie; Tremblay, Zoë; Boulé, Marianne; Lebel, Denis; Major, Philippe; Lortie, Anne; Pinchefsky, Elana; Rossignol, Elsa; Carleton, Bruce; Bussières, Jean-François; Métras, Marie-Élaine.
Afiliación
  • Pépin MA; Pharmacy Practice Research Unit & Department of Pharmacy, CHU Sainte-Justine, Montréal, Québec, H3T 1C5, Canada.
  • Otis AS; Pharmacy Practice Research Unit & Department of Pharmacy, CHU Sainte-Justine, Montréal, Québec, H3T 1C5, Canada.
  • Tremblay Z; Pharmacy Practice Research Unit & Department of Pharmacy, CHU Sainte-Justine, Montréal, Québec, H3T 1C5, Canada.
  • Boulé M; Pharmacy Practice Research Unit & Department of Pharmacy, CHU Sainte-Justine, Montréal, Québec, H3T 1C5, Canada.
  • Lebel D; Pharmacy Practice Research Unit & Department of Pharmacy, CHU Sainte-Justine, Montréal, Québec, H3T 1C5, Canada.
  • Major P; Research Center & Division of Neurology, Department of Pediatrics, CHU Sainte-Justine, Montréal, Québec, H3T 1C5, Canada.
  • Lortie A; Department of Neuroscience, Université de Montréal, Montréal, Québec, H3T 1J4, Canada.
  • Pinchefsky E; Department of Pediatrics, Université de Montréal, Montréal, Québec, H3T 1J4, Canada.
  • Rossignol E; Research Center & Division of Neurology, Department of Pediatrics, CHU Sainte-Justine, Montréal, Québec, H3T 1C5, Canada.
  • Carleton B; Department of Neuroscience, Université de Montréal, Montréal, Québec, H3T 1J4, Canada.
  • Bussières JF; Department of Pediatrics, Université de Montréal, Montréal, Québec, H3T 1J4, Canada.
  • Métras MÉ; Research Center & Division of Neurology, Department of Pediatrics, CHU Sainte-Justine, Montréal, Québec, H3T 1C5, Canada.
Per Med ; 19(5): 423-434, 2022 09.
Article en En | MEDLINE | ID: mdl-35830229
Genetic tests can help predict patients' response to medication. This study aimed to evaluate clinicians' and patients' perceptions of these genetic tests. Pediatric patients, with epilepsy, were tested and completed a survey to assess their perception of these tests. A survey was also completed by their community pharmacists, and virtual discussion groups were held with hospital pharmacists and neurologists. Most participants had a positive view of these tests, with three major themes identified from the discussion groups: receptiveness to testing, test characteristics and integration of tests into practice. The views reported are encouraging for the eventual implementation of these tests in practice, an essential step to improve patient care through personalized medicine.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas de Farmacogenómica / Neurología Tipo de estudio: Observational_studies / Prognostic_studies / Qualitative_research Límite: Child / Humans Idioma: En Revista: Per Med Año: 2022 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas de Farmacogenómica / Neurología Tipo de estudio: Observational_studies / Prognostic_studies / Qualitative_research Límite: Child / Humans Idioma: En Revista: Per Med Año: 2022 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido