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Discovery and Optimization of a Synthetic Class of Nectin-4-Targeted CD137 Agonists for Immuno-oncology.
Upadhyaya, Punit; Kristensson, Julia; Lahdenranta, Johanna; Repash, Elizabeth; Ma, Jun; Kublin, Jessica; Mudd, Gemma E; Luus, Lia; Jeffrey, Phil; Hurov, Kristen; McDonnell, Kevin; Keen, Nicholas.
Afiliación
  • Upadhyaya P; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States.
  • Kristensson J; Bicycle Therapeutics, B900 Building, Babraham Research Campus, Cambridge CB22 3AT, U.K.
  • Lahdenranta J; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States.
  • Repash E; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States.
  • Ma J; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States.
  • Kublin J; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States.
  • Mudd GE; Bicycle Therapeutics, B900 Building, Babraham Research Campus, Cambridge CB22 3AT, U.K.
  • Luus L; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States.
  • Jeffrey P; Bicycle Therapeutics, B900 Building, Babraham Research Campus, Cambridge CB22 3AT, U.K.
  • Hurov K; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States.
  • McDonnell K; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States.
  • Keen N; Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States.
J Med Chem ; 65(14): 9858-9872, 2022 07 28.
Article en En | MEDLINE | ID: mdl-35819182
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos