Cryo-EM reveals mechanisms of angiotensin I-converting enzyme allostery and dimerization.

Lubbe, Lizelle; Sewell, Bryan Trevor; Woodward, Jeremy D; Sturrock, Edward D

Lubbe, Lizelle; Sewell, Bryan Trevor; Woodward, Jeremy D; Sturrock, Edward D.

Afiliación

Lubbe L; Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Sewell BT; Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Woodward JD; Electron Microscope Unit, University of Cape Town, Cape Town, South Africa.
Sturrock ED; Electron Microscope Unit, University of Cape Town, Cape Town, South Africa.

EMBO J ; 41(16): e110550, 2022 08 16.

Article en En | MEDLINE | ID: mdl-35818993

Asunto(s)

Enfermedades Cardiovasculares; Hipertensión; Microscopía por Crioelectrón; Dimerización; Humanos; Peptidil-Dipeptidasa A

Palabras clave

angiotensin I-converting enzyme; cryo-electron microscopy; glycoprotein; homodimerization; zinc metalloprotease

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Hipertensión Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: EMBO J Año: 2022 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Reino Unido

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