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Comparison of retrograde intrarenal stone surgery with and without a ureteral access sheath using kidney injury molecule-1 (KIM-1) levels: a prospective randomized study.
Ecer, Gökhan; Sönmez, Mehmet Giray; Aydin, Arif; Topçu, Cemile; Alalam, Haider Nihad Izaddin; Güven, Selçuk; Balasar, Mehmet.
Afiliación
  • Ecer G; Urology Department, Konya State Hospital, Konya, Turkey. ecergokhan@gmail.com.
  • Sönmez MG; Urology Department, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey.
  • Aydin A; Urology Department, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey.
  • Topçu C; Biochemistry Department, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey.
  • Alalam HNI; Urology Department, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey.
  • Güven S; Urology Department, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey.
  • Balasar M; Urology Department, Necmettin Erbakan University Meram Medical Faculty, Konya, Turkey.
Urolithiasis ; 50(5): 625-633, 2022 Oct.
Article en En | MEDLINE | ID: mdl-35802150
The objective is to compare patients who underwent retrograde intrarenal surgery with and without a ureteral access sheath (UAS) using kidney injury molecule-1 (KIM-1) levels. We also examined the difference in kidney damage between standard and dual lumen UAS. Sixty patients diagnosed with kidney stones and scheduled for RIRS were randomized into three groups: RIRS without UAS (Group 1), 11Fr/13Fr Boston scientific Navigator™ UAS (Group 2), and 11Fr/13Fr dual lumen ClearPetra™ UAS (Group 3). Data were prospectively collected in consecutive patients. Urine KIM-1/Cr levels were measured preoperatively, at postoperative 4 h, and on a postoperative day 14. Stone size, location, number, pre- and postoperative stent use, operation time, stone-free rate (SFR), post-ureteroscopic lesion scale (PULS) grade, hospitalization duration, and complications were recorded. There was no significant difference in demographical parameters and preoperative KIM-1/Cr levels among the groups. Postoperative 4th-hour urine KIM-1/Cr levels were higher in patients without UAS than patients with UAS (1.86, 0.67, 0.63 Groups 1, 2, 3, respectively). In comparing group 1 with groups 2 and 3 separately, Group 1 had a statistically significantly higher value than both groups (p = 0.002, p = 0.001, respectively). According to UAS type, there was no significant difference between groups 2 and 3. The use of UAS during RIRS has been shown to reduce kidney injury in the evaluation with KIM-1. Different UAS types on kidney injury and which one can protect the kidneys more during the procedure; will be elucidated by prospective randomized studies involving larger patient groups and UAS types.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Uréter / Cálculos Renales Tipo de estudio: Observational_studies Límite: Humans Idioma: En Revista: Urolithiasis Año: 2022 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Uréter / Cálculos Renales Tipo de estudio: Observational_studies Límite: Humans Idioma: En Revista: Urolithiasis Año: 2022 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Alemania