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Clinical features and recurrence of Corynebacterium kroppenstedtii infection in patients with mastitis.
Zeng, Weiwei; Lao, Sixian; Jia, Wenbin; Shen, Xintian; Wu, Lijuan; Zhong, Yan; Wang, Feiling; Zhong, Guoping.
Afiliación
  • Zeng W; The Second People's Hospital of Longgang District, Shenzhen, 518112, China.
  • Lao S; Shenzhen Baoan Women's and Children's Hospital, Jinan University, No. 56, Yulv Road, Baoan, Shenzhen, 518102, China.
  • Jia W; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-Sen University, No. 74, Zhongshan 2nd Road, Guangzhou, 510000, China.
  • Shen X; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, 510000, China.
  • Wu L; Shenzhen Baoan Women's and Children's Hospital, Jinan University, No. 56, Yulv Road, Baoan, Shenzhen, 518102, China.
  • Zhong Y; Shenzhen Baoan Women's and Children's Hospital, Jinan University, No. 56, Yulv Road, Baoan, Shenzhen, 518102, China.
  • Wang F; Shenzhen Baoan Women's and Children's Hospital, Jinan University, No. 56, Yulv Road, Baoan, Shenzhen, 518102, China.
  • Zhong G; Shenzhen Baoan Women's and Children's Hospital, Jinan University, No. 56, Yulv Road, Baoan, Shenzhen, 518102, China. xinyuxiongwai@126.com.
BMC Womens Health ; 22(1): 276, 2022 07 06.
Article en En | MEDLINE | ID: mdl-35794560
BACKGROUND: Few studies have investigated the differences in clinical features of patients with mastitis following Corynebacterium kroppenstedtii infection, and most focused on the bacterial antimicrobial susceptibility, detection methods and therapy. METHODOLOGY: There were 133 patients with mastitis infected by C. kroppenstedtii between August 2016 and September 2019. C. kroppenstedtii was identified using mass spectrometry. The demographics, clinical diagnosis, laboratory test results of different types of mastitis combined with bacillus infection, and the effects of different treatments in reducing recurrence were compared. RESULTS: The incidence of pus following C. kroppenstedtii infection was higher in patients with non-granulomatous lobular mastitis (NGLM; 56.6%) than in those with granulomatous lobular mastitis (GLM; 33.3%; χ2 = 7.072, p = 0.008). While C-reactive protein (CRP) was higher in the GLM group (12.50 mg/L) than in the NGLM group (6.05 mg/L; Z = - 2.187, p = 0.029). Treatment with local lavage (triamcinolone acetonide) and antibiotics (cefuroxime) showed a recurrent rate of 25.9% in C. kroppenstedtii infection. CONCLUSION: Increased pus, large masses, and an elevated CRP level may occur in patients with mastitis infected by C.kroppenstedtii. These clinical features may guide the determination of the bacterial infection in patients with mastitis. Combining an antibiotic with a triamcinolone acetonide lavage, preferably cefuroxime, may reduce the recurrence.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Corynebacterium / Mastitis Granulomatosa Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Female / Humans Idioma: En Revista: BMC Womens Health Asunto de la revista: SAUDE DA MULHER Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Corynebacterium / Mastitis Granulomatosa Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Female / Humans Idioma: En Revista: BMC Womens Health Asunto de la revista: SAUDE DA MULHER Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido