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Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: In Vitro, in Vivo, molecular docking, molecular dynamics, and SAR studies.
Hammouda, Mohamed M; Elmaaty, Ayman Abo; Nafie, Mohamed S; Abdel-Motaal, Marwa; Mohamed, Noha S; Tantawy, Mohamed A; Belal, Amany; Alnajjar, Radwan; Eldehna, Wagdy M; Al-Karmalawy, Ahmed A.
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  • Hammouda MM; Department of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia; Department of Chemistry, Faculty of Science, Mansoura University, Mansoura 35516, Egypt. Electronic address: elmhammouda@mans.edu.eg.
  • Elmaaty AA; Department of Medicinal Chemistry, Faculty of Pharmacy, Port Said University, Port Said 42526, Egypt. Electronic address: ayman.mohamed@pharm.psu.edu.eg.
  • Nafie MS; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt. Electronic address: mohamed_nafie@science.suez.edu.eg.
  • Abdel-Motaal M; Department of Chemistry, Faculty of Science, Mansoura University, Mansoura 35516, Egypt; Department of Chemistry, College of Science, Qassim University, Buraydah 51452, Saudi Arabia. Electronic address: dr_marwachem@mans.edu.eg.
  • Mohamed NS; Department of Chemistry, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.
  • Tantawy MA; Hormones Department, Medical Research and Clinical Studies Institute, National Research Centre, Dokki, Giza 12622, Egypt; Stem Cells Lab, Center of Excellence for Advanced Sciences, National Research Centre, Dokki, Giza 12622, Egypt. Electronic address: mohamed_tantawy@daad-alumni.de.
  • Belal A; Medicinal Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
  • Alnajjar R; Department of Chemistry, Faculty of Science, University of Benghazi, Benghazi, Libya; Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa. Electronic address: radwan.alnajjar@uob.edu.ly.
  • Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
  • Al-Karmalawy AA; Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta 34518, Egypt. Electronic address: akarmalawy@horus.edu.eg.
Bioorg Chem ; 127: 105995, 2022 10.
Article en En | MEDLINE | ID: mdl-35792315
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Bioorg Chem Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Bioorg Chem Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos