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Comparison between impulse oscillometry parameters and spirometry for the diagnosis of exercise-induced bronchoconstriction in asthmatic children and adolescents.
Correia Junior, Marco Aurélio de Valois; Filho, Edil de Albuquerque Rodrigues; Tenório, Ricardo César Espinhara; Albuquerque, Claudio Gonçalves de; Barbosa, Laienne Carla; Quirino, Polyanna Guerra Chaves; Sarinho, Emanuel; Medeiros, Décio; Rizzo, José Ângelo.
Afiliación
  • Correia Junior MAV; Center for Research in Allergy and Clinical Immunology, Clinical Hospital, Federal University of Pernambuco, Recife, Brazil.
  • Filho EAR; Postgraduate Program in Hebiatrics, Universidade de Pernambuco, Recife, Brazil.
  • Tenório RCE; Postgraduate Associated Program in Physical Education, Universidade de Pernambuco and Universidade Federal da Paraiba, Recife, Brazil.
  • Albuquerque CG; Center for Research in Allergy and Clinical Immunology, Clinical Hospital, Federal University of Pernambuco, Recife, Brazil.
  • Barbosa LC; Postgraduate Associated Program in Physical Education, Universidade de Pernambuco and Universidade Federal da Paraiba, Recife, Brazil.
  • Quirino PGC; Multicenter Postgraduate Program in Physiological Sciences, Universidade Federal de Pernambuco, Centro Acadêmico de Vitória, Vitória de Santo Antão, Brazil.
  • Sarinho E; Center for Research in Allergy and Clinical Immunology, Clinical Hospital, Federal University of Pernambuco, Recife, Brazil.
  • Medeiros D; Center for Research in Allergy and Clinical Immunology, Clinical Hospital, Federal University of Pernambuco, Recife, Brazil.
  • Rizzo JÂ; Postgraduate Program in Child and Adolescent Health Postgraduate Course, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Pediatr Pulmonol ; 57(10): 2398-2404, 2022 10.
Article en En | MEDLINE | ID: mdl-35791702
INTRODUCTION: Impulse oscillometry (IOS) parameters are obtained more easily and effortlessly in comparison to forced expiratory volume in the first second (FEV1). OBJECTIVE: To compare IOS parameters to FEV1 in exercise-induced bronchoconstriction (EIB) diagnosis. METHODS: Seventy-four (60.8% male; 39.2 female) young asthmatics aged between 7 and 17 years (mean 12.6 ± 2.8 years) were evaluated. EIB was defined as a reduction in FEV1 ≥ 10% compared with basal after standardized challenge by treadmill running (TR). IOS parameters and FEV1 were obtained at baseline and 5,15, and 30 min after TR. The area under the receiver operator characteristic curve (AUC) was calculated from the reduction in FEV1 ≥ 10% to evaluate the best psychometric characteristics of IOS parameters. RESULTS: Twenty-four individuals (32.4%) were diagnosed with EIB. A moderate inverse correlation was found between the IOS and FEV1 variables immediately after the TR, with resistance at 5 Hz (R5Hz), resonant frequency (Fres), and reactance area (AX), (r = -0.64, r = -0.53 and r = -0.69, respectively, all with p < 0.05). An increase of 25 kPa/l/s in R5 Hz, of 19k Pa/l/s in AX and 21 Hz in Fres were found to best correlate with EIB diagnosis by FEV1 (sensitivity 67% and specificity 62%, sensitivity 84% and specificity 50%, and sensitivity 84% and specificity 60%, respectively). CONCLUSION: IOS parameters have a significant inverse correlation with FEV1. This study presents cut-off points for EIB diagnosis for R5Hz, AX, and Fres, however, the findings in IOS parameters should be used and interpreted carefully if the goal is to replace spirometry.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Broncoconstricción Tipo de estudio: Diagnostic_studies Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Pediatr Pulmonol Asunto de la revista: PEDIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Broncoconstricción Tipo de estudio: Diagnostic_studies Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Pediatr Pulmonol Asunto de la revista: PEDIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos