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A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2.
Scoles, Daniel R; Gandelman, Mandi; Paul, Sharan; Dexheimer, Thomas; Dansithong, Warunee; Figueroa, Karla P; Pflieger, Lance T; Redlin, Scott; Kales, Stephen C; Sun, Hongmao; Maloney, David; Damoiseaux, Robert; Henderson, Mark J; Simeonov, Anton; Jadhav, Ajit; Pulst, Stefan M.
Afiliación
  • Scoles DR; Department of Neurology, University of Utah, Salt Lake City, Utah, USA. Electronic address: Daniel.Scoles@hsc.utah.edu.
  • Gandelman M; Department of Neurology, University of Utah, Salt Lake City, Utah, USA.
  • Paul S; Department of Neurology, University of Utah, Salt Lake City, Utah, USA.
  • Dexheimer T; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland, USA.
  • Dansithong W; Department of Neurology, University of Utah, Salt Lake City, Utah, USA.
  • Figueroa KP; Department of Neurology, University of Utah, Salt Lake City, Utah, USA.
  • Pflieger LT; Department of Biomedical Informatics, University of Utah, Salt Lake City, Utah, USA.
  • Redlin S; Department of Neurology, University of Utah, Salt Lake City, Utah, USA.
  • Kales SC; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland, USA.
  • Sun H; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland, USA.
  • Maloney D; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland, USA.
  • Damoiseaux R; Department of Molecular and Medical Pharmacology, Jonsson Comprehensive Cancer Center, California NanoSystems Institute, and Department of Bioengineering in the Samueli School of Engineering, University of California Los Angeles, Los Angeles, California, USA.
  • Henderson MJ; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland, USA.
  • Simeonov A; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland, USA.
  • Jadhav A; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland, USA.
  • Pulst SM; Department of Neurology, University of Utah, Salt Lake City, Utah, USA. Electronic address: Stefan.Pulst@hsc.utah.edu.
J Biol Chem ; 298(8): 102228, 2022 08.
Article en En | MEDLINE | ID: mdl-35787375
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ataxias Espinocerebelosas / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ataxias Espinocerebelosas / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos