Pre-clinical 2D and 3D toxicity response to a panel of nanomaterials; comparative assessment of NBM-induced liver toxicity.

Tutty, Melissa Anne; Vella, Gabriele; Prina-Mello, Adriele

Tutty, Melissa Anne; Vella, Gabriele; Prina-Mello, Adriele.

Afiliación

Tutty MA; Nanomedicine and Molecular Imaging Group, Trinity Translational Medicine Institute (TTMI), School of Medicine, Trinity College Dublin, Dublin 8, Ireland. tuttym@tcd.ie.
Vella G; Laboratory for Biological Characterisation of Advanced Materials (LBCAM), TTMI, School of Medicine, Trinity College Dublin, Dublin 8, Ireland. tuttym@tcd.ie.
Prina-Mello A; Nanomedicine and Molecular Imaging Group, Trinity Translational Medicine Institute (TTMI), School of Medicine, Trinity College Dublin, Dublin 8, Ireland.

Drug Deliv Transl Res ; 12(9): 2157-2177, 2022 09.

Article en En | MEDLINE | ID: mdl-35763196

Asunto(s)

Oro; Nanopartículas del Metal; Animales; Técnicas de Cultivo de Célula/métodos; Oro/farmacología; Humanos; Hígado; Esferoides Celulares

Palabras clave

3D culture; 3Rs; Cytotoxicity; DILI; HepG2; Hepatotoxicity; Liver spheroid; NBMs; Nanobiomaterials; Spheroids; Viability

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nanopartículas del Metal / Oro Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Drug Deliv Transl Res Año: 2022 Tipo del documento: Article País de afiliación: Irlanda Pais de publicación: Estados Unidos

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