Covalently attached intercalators restore duplex stability and splice-switching activity to triazole-modified oligonucleotides.

Dysko, Anna; Baker, Ysobel R; McClorey, Graham; Wood, Matthew J A; Fenner, Sabine; Williams, Glynn; El-Sagheer, Afaf; Brown, Tom

Dysko, Anna; Baker, Ysobel R; McClorey, Graham; Wood, Matthew J A; Fenner, Sabine; Williams, Glynn; El-Sagheer, Afaf; Brown, Tom.

Afiliación

Dysko A; Department of Chemistry, Chemistry Research Laboratory, University of Oxford 12 Mansfield Road Oxford, OX1 3TA UK tom.brown@chem.ox.ac.uk.
Baker YR; Department of Chemistry, Chemistry Research Laboratory, University of Oxford 12 Mansfield Road Oxford, OX1 3TA UK tom.brown@chem.ox.ac.uk.
McClorey G; Department of Physiology, Anatomy and Genetics, University of Oxford Oxford UK.
Wood MJA; Department of Physiology, Anatomy and Genetics, University of Oxford Oxford UK.
Fenner S; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage Hertfordshire SG1 2NY UK.
Williams G; GSK Medicines Research Centre, Gunnels Wood Road, Stevenage Hertfordshire SG1 2NY UK.
El-Sagheer A; Department of Chemistry, Chemistry Research Laboratory, University of Oxford 12 Mansfield Road Oxford, OX1 3TA UK tom.brown@chem.ox.ac.uk.
Brown T; Chemistry Branch Department of Science and Mathematics, Faculty of Petroleum and Mining Engineering, Suez University Suez 43721 Egypt.

RSC Chem Biol ; 3(6): 765-772, 2022 Jun 08.

Article en En | MEDLINE | ID: mdl-35755188

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: RSC Chem Biol Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido

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