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Optimisation of the HepaRG cell line model for drug toxicity studies using two different cultivation conditions: advantages and limitations.
Hammour, Mohammad Majd; Othman, Amnah; Aspera-Werz, Romina; Braun, Bianca; Weis-Klemm, Michaela; Wagner, Silvia; Nadalin, Silvio; Histing, Tina; Ruoß, Marc; Nüssler, Andreas K.
Afiliación
  • Hammour MM; Department of Traumatology, Siegfried Weller Institute, BG Klinik Tübingen, Eberhard Karls University Tübingen, 72076, Tübingen, Germany.
  • Othman A; Department of Traumatology, Siegfried Weller Institute, BG Klinik Tübingen, Eberhard Karls University Tübingen, 72076, Tübingen, Germany.
  • Aspera-Werz R; Department of Traumatology, Siegfried Weller Institute, BG Klinik Tübingen, Eberhard Karls University Tübingen, 72076, Tübingen, Germany.
  • Braun B; Department of Traumatology, Siegfried Weller Institute, BG Klinik Tübingen, Eberhard Karls University Tübingen, 72076, Tübingen, Germany.
  • Weis-Klemm M; Department of General, Visceral and Transplant Surgery, University Hospital Tübingen, 72076, Tübingen, Germany.
  • Wagner S; Department of General, Visceral and Transplant Surgery, University Hospital Tübingen, 72076, Tübingen, Germany.
  • Nadalin S; Department of General, Visceral and Transplant Surgery, University Hospital Tübingen, 72076, Tübingen, Germany.
  • Histing T; Department of Traumatology, Siegfried Weller Institute, BG Klinik Tübingen, Eberhard Karls University Tübingen, 72076, Tübingen, Germany.
  • Ruoß M; Department of Traumatology, Siegfried Weller Institute, BG Klinik Tübingen, Eberhard Karls University Tübingen, 72076, Tübingen, Germany.
  • Nüssler AK; Department of Traumatology, Siegfried Weller Institute, BG Klinik Tübingen, Eberhard Karls University Tübingen, 72076, Tübingen, Germany. andreas.nuessler@med.uni-tuebingen.de.
Arch Toxicol ; 96(9): 2511-2521, 2022 09.
Article en En | MEDLINE | ID: mdl-35748891
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Citocromo P-450 CYP1A2 / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Arch Toxicol Año: 2022 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Citocromo P-450 CYP1A2 / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Arch Toxicol Año: 2022 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania