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Growing Teratoma Syndrome in the Setting of Sarcoidosis: A Case Report and Literature Review.
Shahnam, Adel; Sayer, Robyn; Herbst, Unine; Sharma, Raghwa; Yoon, Won-Hee; Dinihan, Tim; Gao, Bo.
Afiliación
  • Shahnam A; Medical Oncology Department, Blacktown and Westmead Hospitals, Sydney, NSW 2145, Australia.
  • Sayer R; Gynecological Oncology Department, Chris O'Brien Lifehouse, Sydney, NSW 2050, Australia.
  • Herbst U; Gynaecological Oncology Department, Westmead Hospital, Sydney, NSW 2145, Australia.
  • Sharma R; Institute of Clinical Pathology and Medical Research, Westmead Hospital, Sydney, NSW 2145, Australia.
  • Yoon WH; Medical Oncology Department, Blacktown and Westmead Hospitals, Sydney, NSW 2145, Australia.
  • Dinihan T; Respiratory and Thoracic Medicine, Blacktown Hospital, Sydney, NSW 2148, Australia.
  • Gao B; Medical Oncology Department, Blacktown and Westmead Hospitals, Sydney, NSW 2145, Australia.
Curr Oncol ; 29(6): 4148-4154, 2022 06 07.
Article en En | MEDLINE | ID: mdl-35735440
Growing teratoma syndrome (GTS) is rare and can mimic disease recurrence in patients with a history of immature teratoma. Benign hypermetabolic lymphadenopathy found on staging and surveillance computed tomography (CT) and positron emission tomography (PET) may lead to the presumption of metastatic malignancy. We report a case of a 38 year old with mixed mature and immature teratomas who developed new peritoneal masses after adjuvant chemotherapy despite a normalization of tumor markers. In addition to low FDG uptake observed in these peritoneal masses, a PET scan showed hypermetabolic lymphadenopathy and pulmonary and spleen lesions suggesting widespread metastases. Subsequent surgical resection confirmed a mixed pathology with GTS and sarcoidosis. We reviewed the current literature evidence of GTS and sarcoidosis as a benign cause of lymphadenopathy in cancer patients. We emphasize the importance of a tissue diagnosis before instituting therapy for presumed cancer recurrence to avoid potentially fatal diagnostic traps and management errors. A multiple disciplinary team approach is imperative in managing patients with suspected recurrent immature teratomas.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcoidosis / Teratoma / Linfadenopatía Tipo de estudio: Diagnostic_studies Límite: Adult / Humans Idioma: En Revista: Curr Oncol Año: 2022 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcoidosis / Teratoma / Linfadenopatía Tipo de estudio: Diagnostic_studies Límite: Adult / Humans Idioma: En Revista: Curr Oncol Año: 2022 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Suiza