BCL2 G quadruplex-binding small molecules: Current status and prospects for the development of next-generation anticancer therapeutics.

Singh, Mamta; Gupta, Rajat; Comez, Lucia; Paciaroni, Alessandro; Rani, Reshma; Kumar, Vinit

Singh, Mamta; Gupta, Rajat; Comez, Lucia; Paciaroni, Alessandro; Rani, Reshma; Kumar, Vinit.

Afiliación

Singh M; Amity Institute of Molecular Medicine and Stem Cell Research, Amity University, Noida, UP, 201303, India.
Gupta R; Amity Institute of Molecular Medicine and Stem Cell Research, Amity University, Noida, UP, 201303, India.
Comez L; IOM-CNR National Research Council, Via Pascoli, Perugia I-06123, Italy.
Paciaroni A; Department of Physics and Geology, University of Perugia, via Pascoli, 06123, Italy.
Rani R; Drug Discovery Unit, Jubilant Biosys Ltd, Sector 58, Noida, UP 201301, India. Electronic address: reshudcy@gmail.com.
Kumar V; Amity Institute of Molecular Medicine and Stem Cell Research, Amity University, Noida, UP, 201303, India. Electronic address: vkumar25@amity.edu.

Drug Discov Today ; 27(9): 2551-2561, 2022 09.

Article en En | MEDLINE | ID: mdl-35709931

Asunto(s)

G-Cuádruplex; Humanos; Ligandos; Regiones Promotoras Genéticas; Proteínas Proto-Oncogénicas c-bcl-2

Palabras clave

Anticancer therapeutics; BLC2; Drug discovery; G quadruplex; Small molecules; Targeted cancer therapy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: G-Cuádruplex Límite: Humans Idioma: En Revista: Drug Discov Today Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido

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