Discovery of pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives as novel CDK2 inhibitors: synthesis, biological and molecular modeling investigations.

Nassar, Ibrahim F; Abdel Aal, Mohammed T; El-Sayed, Wael A; A E Shahin, Mahmoud; Elsakka, Elsayed G E; Mokhtar, Mahmoud Mohamed; Hegazy, Maghawry; Hagras, Mohamed; Mandour, Asmaa A; Ismail, Nasser S M

Nassar, Ibrahim F; Abdel Aal, Mohammed T; El-Sayed, Wael A; A E Shahin, Mahmoud; Elsakka, Elsayed G E; Mokhtar, Mahmoud Mohamed; Hegazy, Maghawry; Hagras, Mohamed; Mandour, Asmaa A; Ismail, Nasser S M.

Afiliación

Nassar IF; Faculty of Specific Education, Ain Shams University (ASU) 365 Ramsis Street, Abassia Cairo Egypt Dr.ibrahim.nassar@sedu.asu.edu.eg.
Abdel Aal MT; Chemistry Department, Faculty of Science, Menoufia University Shebin El-Kom Egypt.
El-Sayed WA; Department of Chemistry, College of Science, Qassim University Kingdom of Saudi Arabia.
A E Shahin M; Photochemistry Department, National Research Centre El-Behouth St., Dokki Cairo Egypt.
Elsakka EGE; Chemistry Department, Faculty of Science, Menoufia University Shebin El-Kom Egypt.
Mokhtar MM; Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Boys), Al-Azhar University Cairo Egypt.
Hegazy M; Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Boys), Al-Azhar University Cairo Egypt.
Hagras M; Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Boys), Al-Azhar University Cairo Egypt.
Mandour AA; Department of Pharmaceutical Organic Chemistry, College of Pharmacy (Boys), Al-Azhar University Cairo 11884 Egypt.
Ismail NSM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Future University in Egypt (FUE) Cairo 11835 Egypt nasser.saad@fue.edu.eg.

RSC Adv ; 12(23): 14865-14882, 2022 May 12.

Article en En | MEDLINE | ID: mdl-35702208

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: RSC Adv Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido

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