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Energy Dose-Response in Selective Laser Trabeculoplasty: A Review.
Radcliffe, Nathan; Gazzard, Gus; Samuelson, Thomas; Khaw, Peng; Sun, Xinghuai; Aung, Tin; Lam, Dennis; Singh, Kuldev; Katz, L Jay; Aronov, Michael; Sacks, Zachary; Solberg, Yoram; Lindstrom, Richard; Belkin, Michael.
Afiliación
  • Radcliffe N; New York Eye and Ear Infirmary of Mount Sinai, New York, NY.
  • Gazzard G; Moorfields Eye Hospital NHS Foundation Trust.
  • Samuelson T; NIHR Moorfields Biomedical Research Centre.
  • Khaw P; UCL Institute of Ophthalmology, London, UK.
  • Sun X; Minnesota Eye Consultants.
  • Aung T; University of Minnesota Department of Ophthalmology and Visual Neurosciences, Minnesota, MN.
  • Lam D; NIHR Moorfields Biomedical Research Centre.
  • Singh K; UCL Institute of Ophthalmology, London, UK.
  • Katz LJ; Department of Ophthalmology & Visual Science, Eye & ENT Hospital, Shanghai Medical College, Fudan University Shanghai.
  • Aronov M; Singapore Eye Research Institute, Singapore National Eye Centre.
  • Sacks Z; National University of Singapore, Singapore.
  • Solberg Y; C-MER International Eye Research Center of The Chinese University of Hong Kong (Shenzhen), Shenzhen.
  • Lindstrom R; C-MER Dennis Lam & Partners Eye Center, C-MER International Eye Care Group, Hong Kong, China.
  • Belkin M; Stanford University School of Medicine, Stanford, CA.
J Glaucoma ; 31(8): e49-e68, 2022 08 01.
Article en En | MEDLINE | ID: mdl-35701875
PRCIS: A literature review of selective laser trabeculoplasty (SLT) energy dose-response found no definitive relationship between intraocular pressure (IOP) reduction with respect to total or pulse energy, race, pigmentation, or application pattern. PURPOSE: SLT is a safe and effective treatment for lowering IOP. Although evidence is mounting for the advantage of its use as a first-line treatment for IOP reduction, the SLT procedures in use vary widely. The purpose of this literature review was to investigate whether there were any relationships between SLT energy and efficacy for lowering IOP in the published literature. METHODS: A literature review was undertaken that included studies in which energy levels required for successful SLT treatment were investigated: in general, with respect to angle pigmentation, race or ethnicity, and treatment arc extent. RESULTS: There was no indication that higher (or lower) energy used in the treatment leads to greater (or less) IOP reduction. Similar results were obtained regarding the level of trabecular meshwork pigmentation. Race was not found to be associated with altered dose response in SLT. There were indications that treating the full 360 degrees, as opposed to smaller arcs, could be beneficial for more IOP reduction. IOP reduction from SLT was found to be similar to that provided by topical medications. CONCLUSIONS: The optimal energy level of SLT needed for IOP reduction has not yet been definitively established, with all reported pulse energies resulting in similar IOP reduction. Furthermore, similar lack of conclusive findings exists regarding optimal SLT energy dosage for use in different races and degrees of trabecular meshwork pigmentation. This parameter and each of the abovementioned factors requires further research.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trabeculectomía / Hipotensión Ocular / Glaucoma de Ángulo Abierto / Terapia por Láser Límite: Humans Idioma: En Revista: J Glaucoma Asunto de la revista: OFTALMOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trabeculectomía / Hipotensión Ocular / Glaucoma de Ángulo Abierto / Terapia por Láser Límite: Humans Idioma: En Revista: J Glaucoma Asunto de la revista: OFTALMOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos