Reconstitution of Mycobacterium marinum Nonhomologous DNA End Joining Pathway in <i>Leishmania</i>.

Zhang, Wen-Wei; Wright, Douglas G; Harrison, Lynn; Matlashewski, Greg

Reconstitution of Mycobacterium marinum Nonhomologous DNA End Joining Pathway in Leishmania.

Zhang, Wen-Wei; Wright, Douglas G; Harrison, Lynn; Matlashewski, Greg.

Afiliación

Zhang WW; Department of Microbiology and Immunology, McGill Universitygrid.14709.3b, Montreal, Quebec, Canada.
Wright DG; Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Harrison L; Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Matlashewski G; Department of Microbiology and Immunology, McGill Universitygrid.14709.3b, Montreal, Quebec, Canada.

mSphere ; 7(3): e0015622, 2022 06 29.

Article en En | MEDLINE | ID: mdl-35695492

Asunto(s)

Leishmania; Mycobacterium marinum; Animales; ADN; Reparación del ADN por Unión de Extremidades; ADN Ligasa (ATP)/genética; ADN Ligasa (ATP)/metabolismo; Proteínas de Unión al ADN/genética; Humanos; Leishmania/genética; Mamíferos; Mycobacterium marinum/genética; Mycobacterium marinum/metabolismo

Palabras clave

CRISPR-Cas9; DSB repair; Ku; Ku70; Ku80; Leishmania donovani; Ligase D; Mycobacterium marinum; NHEJ; SSA; double-strand DNA break; gene deletion; gene targeting; nonhomologous end joining; single-strand annealing; telomere maintenance

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mycobacterium marinum / Leishmania Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: MSphere Año: 2022 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos

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