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The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression.
Yang, Han; Ting, Xia; Geng, Yue-Hang; Xie, Yuntao; Nierenberg, Jovia L; Huo, Yan-Fei; Zhou, Yan-Ting; Huang, Yang; Yu, Yu-Qing; Yu, Xin-Yao; Li, Xiao-Fei; Ziv, Elad; Zhang, Hongquan; Fang, Wei-Gang; Shen, Yin; Tian, Xin-Xia.
Afiliación
  • Yang H; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
  • Ting X; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA.
  • Geng YH; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
  • Xie Y; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
  • Nierenberg JL; Breast Center, Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing 100142, China.
  • Huo YF; Department of Epidemiology and Biostatistics, University of California, San Francisco School of Medicine, San Francisco, CA, USA.
  • Zhou YT; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
  • Huang Y; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
  • Yu YQ; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
  • Yu XY; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
  • Li XF; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
  • Ziv E; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
  • Zhang H; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA.
  • Fang WG; Division of General Internal Medicine, Department of Medicine, and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.
  • Shen Y; Department of Anatomy, Histology and Embryology, Peking University Health Science Center, Beijing 100191, China.
  • Tian XX; Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), School of Basic Medical Sciences, Peking University Third Hospital, Peking University Health Science Center, Beijing 100191, China.
Sci Adv ; 8(23): eabn3509, 2022 06 10.
Article en En | MEDLINE | ID: mdl-35687692
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estudio de Asociación del Genoma Completo / Netrinas / Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Sci Adv Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estudio de Asociación del Genoma Completo / Netrinas / Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Sci Adv Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos