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Diterpenoid Vinigrol specifically activates ATF4/DDIT3-mediated PERK arm of unfolded protein response to drive non-apoptotic death of breast cancer cells.
Wei, Wencheng; Li, Yunfei; Wang, Chuanxi; Gao, Sanxing; Zhao, Yan; Yang, Zhenyu; Wang, Hao; Gao, Ziying; Jiang, Yanxiang; He, Yuan; Zhao, Li; Gao, Hao; Yao, Xinsheng; Hu, Yuhui.
Afiliación
  • Wei W; Harbin Institute of Technology, Harbin 150000, China; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518005, China; Department of pharmacology, School of Medicine, Southern University of Science and Tec
  • Li Y; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518005, China; Department of pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen 518005, China; Department of Biology
  • Wang C; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy / Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research / International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development o
  • Gao S; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518005, China; Department of pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen 518005, China; Department of Biology
  • Zhao Y; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518005, China; Department of pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen 518005, China; Department of Biology
  • Yang Z; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518005, China; Department of pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen 518005, China; Department of Biology
  • Wang H; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518005, China; Department of pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen 518005, China; Department of Biology
  • Gao Z; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518005, China; Department of pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen 518005, China; Department of Biology
  • Jiang Y; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518005, China; Department of pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen 518005, China; Department of Biology
  • He Y; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518005, China; Department of pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen 518005, China; Department of Biology
  • Zhao L; Department of Head and Neck Surgical Oncology, National Clinical Research Center for Cancer, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100000, China.
  • Gao H; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy / Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research / International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development o
  • Yao X; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy / Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research / International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development o
  • Hu Y; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518005, China; Department of pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen 518005, China; Department of Biology
Pharmacol Res ; 182: 106285, 2022 08.
Article en En | MEDLINE | ID: mdl-35662627
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Diterpenos / Factor de Transcripción Activador 4 / Factor de Transcripción CHOP Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Diterpenos / Factor de Transcripción Activador 4 / Factor de Transcripción CHOP Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos