Mitochondrial Metabolism in Hibernation: Regulation and Implications.

Staples, James F; Mathers, Katherine E; Duffy, Brynne M

Staples, James F; Mathers, Katherine E; Duffy, Brynne M.

Afiliación

Staples JF; Department of Biology, University of Western Ontario, London, Ontario, Canada.
Mathers KE; Department of Biology, University of Western Ontario, London, Ontario, Canada.
Duffy BM; Department of Biology, University of Western Ontario, London, Ontario, Canada.

Physiology (Bethesda) ; 37(5): 0, 2022 09 01.

Article en En | MEDLINE | ID: mdl-35658625

RESUMEN

Hibernators rapidly and reversibly suppress mitochondrial respiration and whole animal metabolism. Posttranslational modifications likely regulate these mitochondrial changes, which may help conserve energy in winter. These modifications are affected by reactive oxygen species (ROS), so suppressing mitochondrial ROS production may also be important for hibernators, just as it is important for surviving ischemia-reperfusion injury.

Asunto(s)

Hibernación; Animales; Metabolismo Energético/fisiología; Hibernación/fisiología; Mitocondrias/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Sciuridae/metabolismo

Palabras clave

ROS; ground squirrel; heterothermy; oxidative phosphorylation; torpor

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hibernación Límite: Animals Idioma: En Revista: Physiology (Bethesda) Asunto de la revista: FISIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos

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