Determinants of Response to Cardiac Resynchronization Therapy.

Allison, John D; Biton, Yitschak; Mela, Theofanie

Allison, John D; Biton, Yitschak; Mela, Theofanie.

Afiliación

Allison JD; The Demoulas Center for Cardiac Arrhythmias, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Biton Y; Cardiac Arrhythmia Service, Hadasssah Medical Center and Hebrew University in Jerusalem Medical School, Jerusalem, Israel.
Mela T; The Demoulas Center for Cardiac Arrhythmias, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.

J Innov Card Rhythm Manag ; 13(5): 4994-5003, 2022 May.

Article en En | MEDLINE | ID: mdl-35655810

RESUMEN

Cardiac resynchronization therapy (CRT) is a well-established treatment modality for ambulatory patients with heart failure (HF) who have prolonged QRS, left bundle branch block, reduced left ventricular (LV) ejection fraction, and New York Heart Association class II-IV. CRT has been shown to induce reverse LV remodeling and improve HF symptoms and clinical outcomes. About one-third of CRT recipients are considered non-responders. Patient selection, LV lead location, LV lead selection, multipoint pacing, and optimization of the atrioventricular and ventriculo-ventricular intervals were all shown to be associated with a better CRT response rate. Herein, we review the determinants of CRT response.

Palabras clave

Cardiac pacing; cardiac resynchronization therapy; heart failure

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Innov Card Rhythm Manag Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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