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Low-intensity extracorporeal shockwave therapy for diabetic men with erectile dysfunction: A systematic scoping review.
Mason, Matthew M; Pai, Raghav K; Masterson, John M; Lokeshwar, Soum D; Chu, Kevin Y; Ramasamy, Ranjith.
Afiliación
  • Mason MM; University of Miami Miller School of Medicine, Miami, Florida, USA.
  • Pai RK; University of Miami Miller School of Medicine, Miami, Florida, USA.
  • Masterson JM; Department of Surgery, Division of Urology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
  • Lokeshwar SD; Department of Urology, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Chu KY; University of Miami Miller School of Medicine, Miami, Florida, USA.
  • Ramasamy R; Desai Sethi Urology Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Andrology ; 11(2): 270-281, 2023 02.
Article en En | MEDLINE | ID: mdl-35642619
BACKGROUND: Erectile dysfunction (ED) is a very common complication in men with diabetes mellitus (DM). Low-intensity extracorporeal shockwave therapy (Li-ESWT) offers a promising nonsurgical treatment option for ED. A systematic scoping review investigating the outcomes of Li-ESWT in diabetic men with ED has not yet been performed. OBJECTIVES: To systematically review animal and clinical studies related to the use of Li-ESWT for treatment of DM-related ED. DATA SOURCES: PubMed, Embase, The Cochrane Library, Scopus, and Web of Science were searched, unrestricted by dates or study design. MATERIALS AND METHODS: We included qualitative studies, quantitative studies, primary research studies, meta-analyses, and research letters written in English. Full text reviewing was completed in all animal and human studies discussing Li-ESWT for the treatment of ED in subjects with DM. Data extracted included the journal citation, publication year, country of origin, study design, and a summary of the pertinent findings. RESULTS: Our search yielded nine clinical studies and 10 animal studies. The results of the clinical studies suggest that Li-ESWT is a safe and effective treatment in men with well-controlled DM and moderate or better ED. However, the benefit is less durable in diabetic men than nondiabetic men. The results of the animal studies suggest that Li-ESWT can significantly improve erectile function in diabetic rat models with ED. CONCLUSIONS: The examined studies present encouraging results for the use of Li-ESWT to treat diabetic men with ED. Future studies, particularly robust randomized controlled trials, are necessary to confirm these findings and provide long-term follow-up.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus / Tratamiento con Ondas de Choque Extracorpóreas / Disfunción Eréctil Tipo de estudio: Clinical_trials / Prognostic_studies / Qualitative_research / Systematic_reviews Límite: Animals / Humans / Male Idioma: En Revista: Andrology Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus / Tratamiento con Ondas de Choque Extracorpóreas / Disfunción Eréctil Tipo de estudio: Clinical_trials / Prognostic_studies / Qualitative_research / Systematic_reviews Límite: Animals / Humans / Male Idioma: En Revista: Andrology Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido