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Ischemia-Modified Albumin-A Potential New Marker of Oxidative Stress in Dermatological Diseases.
Tampa, Mircea; Mitran, Cristina Iulia; Mitran, Madalina Irina; Amuzescu, Andreea; Matei, Clara; Georgescu, Simona Roxana.
Afiliación
  • Tampa M; Department of Dermatology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  • Mitran CI; Department of Dermatology, "Victor Babes" Clinical Hospital for Infectious Diseases, 030303 Bucharest, Romania.
  • Mitran MI; Department of Microbiology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  • Amuzescu A; Department of Microbiology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
  • Matei C; Department of Dermatology, "Victor Babes" Clinical Hospital for Infectious Diseases, 030303 Bucharest, Romania.
  • Georgescu SR; Department of Dermatology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Medicina (Kaunas) ; 58(5)2022 May 17.
Article en En | MEDLINE | ID: mdl-35630086
There is growing evidence that oxidative stress is involved in the pathogenesis of numerous conditions, including dermatological diseases. Various markers are available to assess oxidative stress, but none of these can be considered the ideal marker. Recent studies have shown that ischemia-modified albumin (IMA) is not only an indicator of ischemia, but also a marker of oxidative stress. We have conducted a narrative review to evaluate the role of IMA in dermatological diseases. We have identified 24 original articles that evaluated IMA in skin disorders (psoriasis, acne vulgaris, hidradenitis suppurativa, urticaria, vitiligo and Behcet's disease) and hair disorders (alopecia areata, androgenetic alopecia and telogen effluvium). The results of the studies analyzed reveal that IMA may be considered a new marker of oxidative stress in dermatological diseases and offer new insights into the pathogenesis of these disorders and the theoretical basis for the development of new, effective, targeted therapies. To the best of our knowledge, this is the first review that gathers up data on the role of IMA in dermatological diseases.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de la Piel / Albúmina Sérica Humana / Enfermedades del Cabello Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Medicina (Kaunas) Asunto de la revista: MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de la Piel / Albúmina Sérica Humana / Enfermedades del Cabello Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Medicina (Kaunas) Asunto de la revista: MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: Rumanía Pais de publicación: Suiza