Single-Cell Analyses of a Novel Mouse Urothelial Carcinoma Model Reveal a Role of Tumor-Associated Macrophages in Response to Anti-PD-1 Therapy.

Xu, Dongbo; Wang, Li; Wieczorek, Kyle; Zhang, Yali; Wang, Zinian; Wang, Jianmin; Xu, Bo; Singh, Prashant K; Wang, Yanqing; Zhang, Xiaojing; Wu, Yue; Smith, Gary J; Attwood, Kristopher; Zhang, Yuesheng; Goodrich, David W; Li, Qiang

Xu, Dongbo; Wang, Li; Wieczorek, Kyle; Zhang, Yali; Wang, Zinian; Wang, Jianmin; Xu, Bo; Singh, Prashant K; Wang, Yanqing; Zhang, Xiaojing; Wu, Yue; Smith, Gary J; Attwood, Kristopher; Zhang, Yuesheng; Goodrich, David W; Li, Qiang.

Afiliación

Xu D; Department of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Wang L; Department of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Wieczorek K; Department of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Zhang Y; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Wang Z; Departments of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Wang J; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Xu B; Departments of Pathology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Singh PK; Departments of Cancer Genetics & Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Wang Y; Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Zhang X; Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Wu Y; Department of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Smith GJ; Department of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Attwood K; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Zhang Y; Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Goodrich DW; Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Li Q; Department of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Cancers (Basel) ; 14(10)2022 May 19.

Article en En | MEDLINE | ID: mdl-35626115

Palabras clave

ICI immunotherapy; anti-PD-1; mouse model; mouse urothelial carcinoma; single-cell analyses; tumor-associated macrophages

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Cancers (Basel) Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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