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Multisystem Inflammatory Syndrome in an Adolescent Following SARS-CoV-2 Exposure Despite Three Doses of a COVID-19 Vaccine.
Goel, Anurag Ratan; Chiang, Silvia S; Ibrahim, Osama; Yalcindag, Ali.
Afiliación
  • Goel AR; Departments of Internal Medicine and Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI.
  • Chiang SS; Division of Pediatric Infectious Diseases, Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI.
  • Ibrahim O; Division of Pediatric Infectious Diseases, Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI.
  • Yalcindag A; Division of Pediatric Rheumatology, Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI.
R I Med J (2013) ; 105(5): 41-45, 2022 Jun 01.
Article en En | MEDLINE | ID: mdl-35617041
The multisystem inflammatory syndrome in children (MIS-C) is a known complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the pediatric population. Recent studies have demonstrated high efficacy of a two-dose vaccine series in preventing MIS-C among adolescents. To date, such studies have only included children exposed to SARS-CoV-2 prior to the emergence of the Omicron variant (B.1.1.529). We report a case of an adolescent who received three doses of a vaccine yet developed MIS-C following known exposure to SARS-CoV-2. Given the uncertainty in whether current vaccines offer as much protection against MIS-C due to the Omicron variant or any potential new variants as they have for older variants, pediatric providers should maintain a high index of suspicion for MIS-C regardless of vaccination status.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Respuesta Inflamatoria Sistémica / Enfermedades del Tejido Conjuntivo / COVID-19 Tipo de estudio: Diagnostic_studies Límite: Adolescent / Humans Idioma: En Revista: R I Med J (2013) Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Respuesta Inflamatoria Sistémica / Enfermedades del Tejido Conjuntivo / COVID-19 Tipo de estudio: Diagnostic_studies Límite: Adolescent / Humans Idioma: En Revista: R I Med J (2013) Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos