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Liposomes: structure, composition, types, and clinical applications.
Nsairat, Hamdi; Khater, Dima; Sayed, Usama; Odeh, Fadwa; Al Bawab, Abeer; Alshaer, Walhan.
Afiliación
  • Nsairat H; Pharmacological and Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, 19328, Jordan.
  • Khater D; Department of Chemistry, Faculty of Arts and Science, Applied Science Private University, Amman, Jordan.
  • Sayed U; Department of Biology, The University of Jordan, Amman, 11942, Jordan.
  • Odeh F; Department of Chemistry, The University of Jordan, Amman, 11942, Jordan.
  • Al Bawab A; Department of Chemistry, The University of Jordan, Amman, 11942, Jordan.
  • Alshaer W; Hamdi Mango Center for Scientific Research, The University of Jordan, Amman, 11942, Jordan.
Heliyon ; 8(5): e09394, 2022 May.
Article en En | MEDLINE | ID: mdl-35600452
Liposomes are now considered the most commonly used nanocarriers for various potentially active hydrophobic and hydrophilic molecules due to their high biocompatibility, biodegradability, and low immunogenicity. Liposomes also proved to enhance drug solubility and controlled distribution, as well as their capacity for surface modifications for targeted, prolonged, and sustained release. Based on the composition, liposomes can be considered to have evolved from conventional, long-circulating, targeted, and immune-liposomes to stimuli-responsive and actively targeted liposomes. Many liposomal-based drug delivery systems are currently clinically approved to treat several diseases, such as cancer, fungal and viral infections; more liposomes have reached advanced phases in clinical trials. This review describes liposomes structure, composition, preparation methods, and clinical applications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2022 Tipo del documento: Article País de afiliación: Jordania Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2022 Tipo del documento: Article País de afiliación: Jordania Pais de publicación: Reino Unido