Long non-coding RNA MALAT1 protects against Aß<sub>1-42</sub> induced toxicity by regulating the expression of receptor tyrosine kinase EPHA2 via quenching miR-200a/26a/26b in Alzheimer's disease.

Chanda, Kaushik; Jana, Nihar Ranjan; Mukhopadhyay, Debashis

Long non-coding RNA MALAT1 protects against Aß_1-42 induced toxicity by regulating the expression of receptor tyrosine kinase EPHA2 via quenching miR-200a/26a/26b in Alzheimer's disease.

Chanda, Kaushik; Jana, Nihar Ranjan; Mukhopadhyay, Debashis.

Afiliación

Chanda K; Biophysics and Structural Genomics Division, Saha Institute of Nuclear Physics, HBNI, Kolkata 700 064, India; Department of Neuroscience, UF Scripps Biomedical Research, 120 Scripps Way, Jupiter, FL 33458, United States of America.
Jana NR; Cellular and Molecular Neuroscience Laboratory, National Brain Research Centre, Manesar, Gurgaon 122 050, India.
Mukhopadhyay D; Biophysics and Structural Genomics Division, Saha Institute of Nuclear Physics, HBNI, Kolkata 700 064, India. Electronic address: debashis.mukhopadhyay@saha.ac.in.

Life Sci ; 302: 120652, 2022 Aug 01.

Article en En | MEDLINE | ID: mdl-35598655

Asunto(s)

Enfermedad de Alzheimer; MicroARNs; ARN Largo no Codificante; Animales; Humanos; Ratones; Enfermedad de Alzheimer/metabolismo; MicroARNs/genética; MicroARNs/metabolismo; Proteínas Tirosina Quinasas Receptoras/genética; ARN Largo no Codificante/metabolismo; Receptor EphA2

Palabras clave

Alzheimer's disease; Long non-coding RNA; MALAT1; Receptor tyrosine kinase; micro-RNA

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: MicroARNs / Enfermedad de Alzheimer / ARN Largo no Codificante Límite: Animals / Humans Idioma: En Revista: Life Sci Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos

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