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Metabolic syndrome in calcium oxalate stones: Is it so important in this type of lithiasis?
Laso García, I; Gomez Dos Santos, V; Sánchez Herranz, A; Duque Ruiz, G; Arias Fúnez, F; Hevia Palacios, M; Burgos Revilla, F J.
Afiliación
  • Laso García I; Departamento de Urología, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, Spain. Electronic address: ines.laso.garcia@gmail.com.
  • Gomez Dos Santos V; Departamento de Urología, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, Spain.
  • Sánchez Herranz A; Departamento de Bioquímica, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, Spain.
  • Duque Ruiz G; Departamento de Urología, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, Spain.
  • Arias Fúnez F; Departamento de Urología, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, Spain.
  • Hevia Palacios M; Departamento de Urología, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, Spain.
  • Burgos Revilla FJ; Departamento de Urología, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, Spain.
Actas Urol Esp (Engl Ed) ; 46(5): 317-322, 2022 06.
Article en En, Es | MEDLINE | ID: mdl-35570101
INTRODUCTION AND OBJECTIVE: The association of the metabolic syndrome with lithogenesis has been described, especially in uric acid stones. The aim of the work was to analyze the role of the metabolic syndrome in oxalocalcic lithogenesis. MATERIALS AND METHODS: Metabolic evaluation of 151 patients including biochemical, hormonal and 24-urine urine parameters, as well as characteristics associated with metabolic syndrome. The relationship between the characteristics associated with the metabolic syndrome and those related to lithogenesis was evaluated using Spearman's correlation coefficient (SCC), Student's t test and Fisher's exact test. RESULTS: The average body mass index (BMI) was 25.9 (SD 3.7). The median age was 51 years (18.6-84.8) and 64.9% were men. There were no statistically significant differences between hypertension and estradiol, testosterone, triglycerides or cholesterol (P=.191, .969, .454, .345, respectively). Regarding glucose, the mean was 114.5 and 93.5mg/dl in patients with and without hypertension (P=.000). The levels of glucose, estradiol, testosterone or cholesterol did not vary with proteinuria (P=.518, P=.227, P=.095, P=.218, respectively). The mean triglycerides were 185.6 and 108.2mg/dl in patients with and without proteinuria (P=.001). Hypertension and proteinuria were not associated (P=.586). BMI correlated with serum and urinary uric acid and urinary creatinine. CONCLUSIONS: There are few associations between the characteristics of the metabolic syndrome and the anomalies related to lithogenesis. Metabolic syndrome does not seem to have a relevant role in the development of oxalocalcic stones.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Litiasis / Síndrome Metabólico / Hipertensión Límite: Female / Humans / Male / Middle aged Idioma: En / Es Revista: Actas Urol Esp (Engl Ed) Año: 2022 Tipo del documento: Article Pais de publicación: España
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Litiasis / Síndrome Metabólico / Hipertensión Límite: Female / Humans / Male / Middle aged Idioma: En / Es Revista: Actas Urol Esp (Engl Ed) Año: 2022 Tipo del documento: Article Pais de publicación: España