Identification of Potential Anti-Neuroinflammatory Inhibitors from Antarctic Fungal Strain <i>Aspergillus</i> sp. SF-7402 via Regulating the NF-&#954;B Signaling Pathway in Microglia.

Cao, Thao Quyen; Liu, Zhiming; Dong, Linsha; Lee, Hwan; Ko, Wonmin; Vinh, Le Ba; Tuan, Nguyen Quoc; Kim, Youn-Chul; Sohn, Jae Hak; Yim, Joung Han; Lee, Dong-Sung; Oh, Hyuncheol

Identification of Potential Anti-Neuroinflammatory Inhibitors from Antarctic Fungal Strain Aspergillus sp. SF-7402 via Regulating the NF-κB Signaling Pathway in Microglia.

Cao, Thao Quyen; Liu, Zhiming; Dong, Linsha; Lee, Hwan; Ko, Wonmin; Vinh, Le Ba; Tuan, Nguyen Quoc; Kim, Youn-Chul; Sohn, Jae Hak; Yim, Joung Han; Lee, Dong-Sung; Oh, Hyuncheol.

Afiliación

Cao TQ; Institute of Pharmaceutical Research and Development, College of Pharmacy, Wonkwang University, Iksan 54538, Korea.
Liu Z; Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, Iksan 54538, Korea.
Dong L; College of Pharmacy, Chosun University, Dong-gu, Gwangju 61452, Korea.
Lee H; College of Pharmacy, Chosun University, Dong-gu, Gwangju 61452, Korea.
Ko W; College of Pharmacy, Chosun University, Dong-gu, Gwangju 61452, Korea.
Vinh LB; College of Pharmacy, Chosun University, Dong-gu, Gwangju 61452, Korea.
Tuan NQ; Institute of Pharmaceutical Research and Development, College of Pharmacy, Wonkwang University, Iksan 54538, Korea.
Kim YC; Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, Iksan 54538, Korea.
Sohn JH; Institute of Pharmaceutical Research and Development, College of Pharmacy, Wonkwang University, Iksan 54538, Korea.
Yim JH; Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, Iksan 54538, Korea.
Lee DS; Institute of Pharmaceutical Research and Development, College of Pharmacy, Wonkwang University, Iksan 54538, Korea.
Oh H; College of Medical and Life Sciences, Silla University, Busan 46958, Korea.

Molecules ; 27(9)2022 Apr 29.

Article en En | MEDLINE | ID: mdl-35566201

Asunto(s)

Microglía; FN-kappa B; Regiones Antárticas; Antiinflamatorios/química; Aspergillus/metabolismo; Interleucina-6/metabolismo; Lipopolisacáridos/metabolismo; Lipopolisacáridos/farmacología; FN-kappa B/metabolismo; Óxido Nítrico/metabolismo; Óxido Nítrico Sintasa de Tipo II/metabolismo; Transducción de Señal; Esterigmatocistina/metabolismo; Esterigmatocistina/farmacología; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Antarctica; BV2 cells; NF-κB; fungi metabolites; neuroinflammation; sterigmatocystin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: FN-kappa B / Microglía Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Suiza

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