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A Combined Human in Silico and CRISPR/Cas9-Mediated in Vivo Zebrafish Based Approach to Provide Phenotypic Data for Supporting Early Target Validation.
Winter, Matthew J; Ono, Yosuke; Ball, Jonathan S; Walentinsson, Anna; Michaelsson, Erik; Tochwin, Anna; Scholpp, Steffen; Tyler, Charles R; Rees, Steve; Hetheridge, Malcolm J; Bohlooly-Y, Mohammad.
Afiliación
  • Winter MJ; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
  • Ono Y; Living Systems Institute, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
  • Ball JS; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
  • Walentinsson A; Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Michaelsson E; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Tochwin A; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
  • Scholpp S; Living Systems Institute, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
  • Tyler CR; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
  • Rees S; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
  • Hetheridge MJ; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
  • Bohlooly-Y M; Translational Genomics, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Front Pharmacol ; 13: 827686, 2022.
Article en En | MEDLINE | ID: mdl-35548346
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Suiza