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Association analysis for SNPs of MSTN and IGFBP-3 genes with body size and other production traits in Liaoning Cashmere Goats.
Sun, Yinggang; Cai, Weidong; Zhang, Xinjiang; Hui, Taiyu; Xu, Yanan; Han, Di; Dou, Xingtang; Wang, Zhanhong; Wang, Jiaming; Lin, Guangyu; Wang, Lingling; Hao, Jianjun; Fu, Shuqing; Wu, Yanzhi; Chen, Rui; Qin, Yuting; Zhang, Yu; Gu, Ming; Bai, Zhixian; Wang, Zeying.
Afiliación
  • Sun Y; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Cai W; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Zhang X; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Hui T; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Xu Y; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Han D; Liaoning Province Modern Agricultural Production Base Construction Engineering Center, Shenyang, China.
  • Dou X; Liaoning Province Modern Agricultural Production Base Construction Engineering Center, Shenyang, China.
  • Wang Z; Liaoning Province Modern Agricultural Production Base Construction Engineering Center, Shenyang, China.
  • Wang J; Liaoning Province Modern Agricultural Production Base Construction Engineering Center, Shenyang, China.
  • Lin G; Liaoning Province Modern Agricultural Production Base Construction Engineering Center, Shenyang, China.
  • Wang L; Liaoning Province Modern Agricultural Production Base Construction Engineering Center, Shenyang, China.
  • Hao J; Administration Bureau of Zhungeer Banner, Erdos City, China.
  • Fu S; Lantian Sub-district Office, Zhungeer Banner, Ordos City, China.
  • Wu Y; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Chen R; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Qin Y; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Zhang Y; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Gu M; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Bai Z; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
  • Wang Z; College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
Anim Biotechnol ; 34(5): 1796-1806, 2023 Nov.
Article en En | MEDLINE | ID: mdl-35507891
Liaoning cashmere goat (LCG) have tall bones, high cashmere production and outstanding meat production performance. In recent years, good breeding progress has not been made in terms of body size, meat yield, milk yield and other properties in terms of production. The study focused on the correlation between the SNPs of MSTN and IGFBP-3 genes with the body size performance, cashmere production and milk performance. The MSTN and IGFBP-3 gene sequence alignment and PCR-Seq polymorphism were used to detect the potential SNPs, and the correlation with production performance was analyzed by SPSS and SHEsis software. The results showed that the TT genotype at the T1662G locus of the MSTN gene is dominant and has significant advantages in body measurements such as sacrum height, chest width, and waist height. The C allele at the C4021T locus of IGFBP-3 gene shows an advantage in the body measurement performance. Among the haplotype combinations, H2H2:TGTC is preponderant combination for body size performance, H2H2:TGTC and H1H2:TGCC are preponderant combinations for cashmere production performance, H1H3:GGCC is preponderant combination for milk production performance. It may be a molecular marker for future selection and breeding.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína 3 de Unión a Factor de Crecimiento Similar a la Insulina / Polimorfismo de Nucleótido Simple Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Anim Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína 3 de Unión a Factor de Crecimiento Similar a la Insulina / Polimorfismo de Nucleótido Simple Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Anim Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido