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An aptamer agonist of the insulin receptor acts as a positive or negative allosteric modulator, depending on its concentration.
Yunn, Na-Oh; Lee, Jimin; Lee, Hye Sun; Oh, Eun Ju; Park, Mangeun; Park, Seongeun; Jin, Seo Yeon; Shin, Euisu; Lee, Jo Woon Yi; Kim, Youndong; Bae, Sun Sik; Ryu, Sung Ho.
Afiliación
  • Yunn NO; Postech Biotech Center, Pohang University of Science and Technology (POSTECH), Pohang, 37673, Republic of Korea.
  • Lee J; The Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, 37673, Republic of Korea.
  • Lee HS; Department of Pharmacology, School of Medicine, Pusan National University, Yangsan, 50612, Republic of Korea.
  • Oh EJ; Postech Biotech Center, Pohang University of Science and Technology (POSTECH), Pohang, 37673, Republic of Korea.
  • Park M; Postech Biotech Center, Pohang University of Science and Technology (POSTECH), Pohang, 37673, Republic of Korea.
  • Park S; Postech Biotech Center, Pohang University of Science and Technology (POSTECH), Pohang, 37673, Republic of Korea.
  • Jin SY; Department of Pharmacology, School of Medicine, Pusan National University, Yangsan, 50612, Republic of Korea.
  • Shin E; Aptamer Sciences, Inc., Seongnam, 13605, Republic of Korea.
  • Lee JWY; Aptamer Sciences, Inc., Seongnam, 13605, Republic of Korea.
  • Kim Y; Aptamer Sciences, Inc., Seongnam, 13605, Republic of Korea.
  • Bae SS; Department of Pharmacology, School of Medicine, Pusan National University, Yangsan, 50612, Republic of Korea. sunsik@pusan.ac.kr.
  • Ryu SH; The Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, 37673, Republic of Korea. sungho@postech.ac.kr.
Exp Mol Med ; 54(4): 531-541, 2022 04.
Article en En | MEDLINE | ID: mdl-35478209
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptor de Insulina / Diabetes Mellitus Experimental Límite: Animals Idioma: En Revista: Exp Mol Med Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptor de Insulina / Diabetes Mellitus Experimental Límite: Animals Idioma: En Revista: Exp Mol Med Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos