Design and optimization of silymarin loaded in lyophilized fast melt tablets to attenuate lung toxicity induced <i>via</i> HgCl<sub>2</sub> in rats.

Sheta, Nermin M; Boshra, Sylvia A; Mamdouh, Mohamed A; Abdel-Haleem, Khaled M

Design and optimization of silymarin loaded in lyophilized fast melt tablets to attenuate lung toxicity induced via HgCl₂ in rats.

Sheta, Nermin M; Boshra, Sylvia A; Mamdouh, Mohamed A; Abdel-Haleem, Khaled M.

Afiliación

Sheta NM; Pharmaceutics Department, Faculty of Pharmacy, October 6 University, Giza, Egypt.
Boshra SA; Biochemistry Department, Faculty of Pharmacy, October 6 University, Giza, Egypt.
Mamdouh MA; Pharmaceutics Department, Faculty of Pharmacy, October 6 University, Giza, Egypt.
Abdel-Haleem KM; Pharmaceutics Department, Faculty of Pharmacy, October 6 University, Giza, Egypt.

Drug Deliv ; 29(1): 1299-1311, 2022 Dec.

Article en En | MEDLINE | ID: mdl-35470762

Asunto(s)

MicroARNs; Silimarina; Administración Oral; Animales; Humanos; Pulmón; Ratas; Silimarina/química; Silimarina/farmacología; Solubilidad; Espectroscopía Infrarroja por Transformada de Fourier/métodos; Comprimidos/química

Palabras clave

COX-2; Silymarin; fast melt tablets; lung toxicity; lyophilization; miRNA 133a; miRNA155

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Silimarina / MicroARNs Tipo de estudio: Guideline Límite: Animals / Humans Idioma: En Revista: Drug Deliv Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2022 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Reino Unido

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