LncRNA FLG-AS1 Mitigates Diabetic Retinopathy by Regulating Retinal Epithelial Cell Inflammation, Oxidative Stress, and Apoptosis via miR-380-3p/SOCS6 Axis.

Luo, Rong; Li, Lan; Xiao, Fan; Fu, Jinsong

Luo, Rong; Li, Lan; Xiao, Fan; Fu, Jinsong.

Afiliación

Luo R; Department of ophthalmology, The First Affiliated Hospital of Nanchang Medical college, Jiangxi Provincial People's Hospital, No. 92, Aiguo Road, Nanchang, Jiangxi, 330006, People's Republic of China. 13677081973@163.com.
Li L; Department of ophthalmology, The First Affiliated Hospital of Nanchang Medical college, Jiangxi Provincial People's Hospital, No. 92, Aiguo Road, Nanchang, Jiangxi, 330006, People's Republic of China.
Xiao F; Department of ophthalmology, The First Affiliated Hospital of Nanchang Medical college, Jiangxi Provincial People's Hospital, No. 92, Aiguo Road, Nanchang, Jiangxi, 330006, People's Republic of China.
Fu J; Department of ophthalmology, The First Affiliated Hospital of Nanchang Medical college, Jiangxi Provincial People's Hospital, No. 92, Aiguo Road, Nanchang, Jiangxi, 330006, People's Republic of China.

Inflammation ; 45(5): 1936-1949, 2022 Oct.

Article en En | MEDLINE | ID: mdl-35461393

Asunto(s)

Diabetes Mellitus Experimental; Retinopatía Diabética; MicroARNs; ARN Largo no Codificante; Animales; Apoptosis; Proliferación Celular; Diabetes Mellitus Experimental/metabolismo; Retinopatía Diabética/genética; Retinopatía Diabética/metabolismo; Eosina Amarillenta-(YS)/metabolismo; Células Epiteliales/metabolismo; Glucosa/metabolismo; Hematoxilina/metabolismo; Humanos; Inflamación/metabolismo; Interleucina-6/metabolismo; MicroARNs/genética; MicroARNs/metabolismo; Estrés Oxidativo; ARN Largo no Codificante/metabolismo; Ratas; Especies Reactivas de Oxígeno/metabolismo; Pigmentos Retinianos/metabolismo; Estreptozocina/metabolismo; Superóxido Dismutasa/metabolismo; Proteínas Supresoras de la Señalización de Citocinas; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

FLG-AS1; SOCS6; apoptosis.; diabetic retinopathy; inflammation; miR-380-3p; oxidative stress

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: MicroARNs / Diabetes Mellitus Experimental / Retinopatía Diabética / ARN Largo no Codificante Límite: Animals / Humans Idioma: En Revista: Inflammation Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos

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