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An Unusual Case of Deep Localized Scleroderma in a Patient with Chronic Kidney Disease.
Rodriguez-Baisi, Katinna E; Santaliz-Ruiz Iv, Luis E; Diaz-Martinez, Angel J; Pagan, Angel D; Sánchez, Nestor P; Villa, Jaime.
Afiliación
  • Rodriguez-Baisi KE; Ponce Health Sciences University School of Medicine, Ponce, PR.
  • Santaliz-Ruiz Iv LE; Department of Dermatology, University of Puerto Rico School of Medicine, San Juan, PR.
  • Diaz-Martinez AJ; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Pagan AD; Ponce Health Sciences University School of Medicine, Ponce, PR.
  • Sánchez NP; Ponce Health Sciences University School of Medicine, Ponce, PR.
  • Villa J; Ponce Health Sciences University School of Medicine, Ponce, PR.
P R Health Sci J ; 41(1): 45-48, 2022 03 17.
Article en En | MEDLINE | ID: mdl-35438896
Localized scleroderma (LS) is a rare fibrosing disorder of skin and underlying tissues. Although it can affect all races, it has a higher prevalence in whites. Deep LS is the least common among seven LS variants, representing less than 5% of cases, and typically affects areas of pressure such as the hips and waist. We report a unique clinical case of bilateral lower extremity deep LS in a 51-year-old Puerto Rican woman with chronic kidney disease (CKD). In patients with CKD, it is important to distinguish LS from nephrogenic systemic fibrosis (NSF). Both can present with skin fibrosis and contractures over joints yet have significantly differing treatment approaches and prognosis. Our case report is unique due to the patient's Puerto Rican ethnicity, CKD history, and isolated anterior lower extremity involvement. In this report, we highlight key clinical and histopathological findings of LS, and how they differ from that of NSF.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esclerodermia Localizada / Enfermedades de la Piel / Insuficiencia Renal Crónica / Dermopatía Fibrosante Nefrogénica Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: P R Health Sci J Año: 2022 Tipo del documento: Article Pais de publicación: Puerto Rico
Buscar en Google
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esclerodermia Localizada / Enfermedades de la Piel / Insuficiencia Renal Crónica / Dermopatía Fibrosante Nefrogénica Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: P R Health Sci J Año: 2022 Tipo del documento: Article Pais de publicación: Puerto Rico