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Evaluation of deltamethrin-loaded Zn-Fe, Zn-Al-GA layered double hydroxide, and Fe-O nanoparticles against resistant Rhipicephalus annulatus ticks.
Aboelhadid, Shawky M; Ibrahium, Samar M; Wahba, Ahmed A; Farghali, Ahmed A.
Afiliación
  • Aboelhadid SM; Department of Parasitology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, Egypt.
  • Ibrahium SM; Department of Parasitology, Animal Health Research Institute, Fayum Branch, Fayum, Egypt.
  • Wahba AA; Department of Parasitology, Animal Health Research Institute, Dokki, Egypt.
  • Farghali AA; Materials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni- Suef University, Beni-Suef, Egypt.
Ann Parasitol ; 68(1): 23-34, 2022.
Article en En | MEDLINE | ID: mdl-35436398
The over use of deltamethrin has resulted in the development of resistance. Thus, the search for a new method to improve its acaricidal effect is the target of the present study. Layered double hydroxide (LDH) compounds are now used as drug delivery systems. Deltamethrin (Butox®) was loaded on Zn-Fe LDH, Zn-Al-GA layered double hydroxide (LDH), and Fe-oxide nanoparticles NPs. Then its acaricidal efficacy was evaluated. The nanocomposites (NCs) were prepared by the co-precipitation method and characterized before and after deltamethrin loading. The deltamethrin-loaded NCs were applied against the phenotypically resistant Rhipicephalus annulatus tick (adult and larvae). The adult ticks treated by Butox® alone or Butox® loaded nanocomposites at different concentrations showed no mortality. A significant (P≤0.05) reduction in egg production index was observed at the recommended dose (X) (1 µl/ml distilled water) and its bi-folds (2X, 3X, and 4X) in ticks treated with deltamethrin/Zn-Fe LDH nanocomposites compared to deltamethrin alone. Moreover, no significant difference (P>0.05) was recorded in larval mortality between the treatments with deltamethrin alone and its loaded nanocomposites. Also, the nanomaterials alone without conjugation with deltamethrin revealed a low mortality rate. Deltamethrin-loaded nanocomposites even improve effect against adult tick but cannot overcome tick resistance to deltamethrin that needs more search. The acaricidal activity of deltamethrin was not improved after loading it with these nanocomposites.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rhipicephalus / Nanopartículas / Acaricidas Límite: Animals Idioma: En Revista: Ann Parasitol Año: 2022 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Polonia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rhipicephalus / Nanopartículas / Acaricidas Límite: Animals Idioma: En Revista: Ann Parasitol Año: 2022 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Polonia