A Recombinant Alpha-Like Protein Subunit Vaccine (GBS-NN) Provides Protection in Murine Models of Group B Streptococcus Infection.

Brokaw, Alyssa; Nguyen, Shayla; Quach, Phoenicia; Orvis, Austyn; Furuta, Anna; Johansson-Lindbom, Bengt; Fischer, Per B; Rajagopal, Lakshmi

Brokaw, Alyssa; Nguyen, Shayla; Quach, Phoenicia; Orvis, Austyn; Furuta, Anna; Johansson-Lindbom, Bengt; Fischer, Per B; Rajagopal, Lakshmi.

Afiliación

Brokaw A; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Nguyen S; Department of Global Health, University of Washington, Seattle, Washington, USA.
Quach P; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Orvis A; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Furuta A; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Johansson-Lindbom B; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Fischer PB; Department of Global Health, University of Washington, Seattle, Washington, USA.
Rajagopal L; MinervaX A/S, Copenhagen, Denmark.

J Infect Dis ; 226(1): 177-187, 2022 08 12.

Article en En | MEDLINE | ID: mdl-35429401

Asunto(s)

Complicaciones Infecciosas del Embarazo; Infecciones Estreptocócicas; Vacunas Estreptocócicas; Adulto; Animales; Modelos Animales de Enfermedad; Femenino; Humanos; Ratones; Embarazo; Complicaciones Infecciosas del Embarazo/prevención & control; Subunidades de Proteína; Infecciones Estreptocócicas/prevención & control; Streptococcus; Streptococcus agalactiae; Vacunas de Subunidad

Palabras clave

Streptococcus agalactiae; Rib; alpha-like proteins; group B Streptococcus; intranasal infection; maternal vaccination; neonate; pregnancy; surface proteins; vaccine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Infecciosas del Embarazo / Infecciones Estreptocócicas / Vacunas Estreptocócicas Tipo de estudio: Prognostic_studies Límite: Adult / Animals / Female / Humans / Pregnancy Idioma: En Revista: J Infect Dis Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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