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Increased Risk for Thromboembolism After Fontan Surgery: Considerations for Thromboprophylaxis.
Van Den Helm, Suelyn; Sparks, Christopher Noel; Ignjatovic, Vera; Monagle, Paul; Attard, Chantal.
Afiliación
  • Van Den Helm S; Haematology Research, Murdoch Children's Research Institute, Melbourne, VIC, Australia.
  • Sparks CN; Department of Paediatrics, The University of Melbourne, Melbourne, VIC, Australia.
  • Ignjatovic V; Haematology Research, Murdoch Children's Research Institute, Melbourne, VIC, Australia.
  • Monagle P; Department of Anatomy and Physiology, The University of Melbourne, Melbourne, VIC, Australia.
  • Attard C; Haematology Research, Murdoch Children's Research Institute, Melbourne, VIC, Australia.
Front Pediatr ; 10: 803408, 2022.
Article en En | MEDLINE | ID: mdl-35419321
The Fontan circulation introduces an increased risk of thromboembolism which is associated with substantial mortality and morbidity. Adverse outcomes of thromboembolic complications post-Fontan surgery vary in both nature and severity, ranging from local tissue infarction and pulmonary embolism to Fontan failure and ischemic stroke. Furthermore, recent studies have identified that subclinical stroke is common yet underdiagnosed in Fontan patients. Fontan patients are commonly treated with antiplatelet agents and/or anticoagulants as primary thromboprophylaxis. Optimal thromboprophylaxis management in the Fontan population is still unclear, and clinical consensus remains elusive despite the growing literature on the subject. This perspective will describe the nature of thromboembolism post-Fontan surgery and provide evidence for the use of both current and emerging thromboprophylaxis options for children and adults living with Fontan circulation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Risk_factors_studies Idioma: En Revista: Front Pediatr Año: 2022 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Risk_factors_studies Idioma: En Revista: Front Pediatr Año: 2022 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Suiza