Butyrate supplementation regulates expression of chromosome segregation 1­like protein to reverse the genetic distortion caused by p53 mutations in colorectal cancer.

Chang, Chun-Chao; Kao, Wei-Yu; Liu, Chih-Yi; Su, Hui-Hsien; Kan, Yu-An; Lin, Pao-Ying; Ku, Wei-Chi; Chang, Kang-Wei; Yang, Ruey-Neng; Huang, Chi-Jung

Butyrate supplementation regulates expression of chromosome segregation 1like protein to reverse the genetic distortion caused by p53 mutations in colorectal cancer.

Chang, Chun-Chao; Kao, Wei-Yu; Liu, Chih-Yi; Su, Hui-Hsien; Kan, Yu-An; Lin, Pao-Ying; Ku, Wei-Chi; Chang, Kang-Wei; Yang, Ruey-Neng; Huang, Chi-Jung.

Afiliación

Chang CC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 11031, Taiwan, R.O.C.
Kao WY; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 11031, Taiwan, R.O.C.
Liu CY; Department of Pathology, Sijhih Cathay General Hospital, New Taipei 22174, Taiwan, R.O.C.
Su HH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 11031, Taiwan, R.O.C.
Kan YA; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 11031, Taiwan, R.O.C.
Lin PY; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 11031, Taiwan, R.O.C.
Ku WC; School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 24205, Taiwan, R.O.C.
Chang KW; Neuroscience Research Center, Taipei Medical University, Taipei 11031, Taiwan, R.O.C.
Yang RN; School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 24205, Taiwan, R.O.C.
Huang CJ; Department of Medical Research, Cathay General Hospital, Taipei 10630, Taiwan, R.O.C.

Int J Oncol ; 60(6)2022 Jun.

Article en En | MEDLINE | ID: mdl-35417036

Asunto(s)

Butiratos; Proteína de Susceptibilidad a Apoptosis Celular; Neoplasias Colorrectales; Proteína p53 Supresora de Tumor; Animales; Apoptosis; Butiratos/farmacología; Células CACO-2; Proliferación Celular; Proteína de Susceptibilidad a Apoptosis Celular/genética; Segregación Cromosómica; Neoplasias Colorrectales/tratamiento farmacológico; Neoplasias Colorrectales/genética; Neoplasias Colorrectales/patología; Suplementos Dietéticos; Células HCT116; Humanos; Ratones; Mutación; Proteína p53 Supresora de Tumor/genética; Proteína p53 Supresora de Tumor/metabolismo

Palabras clave

butyricicoccus pullicaecorum; chromosome segregation 1like; colorectal cancer; p53 tumor suppressor; shortchain fatty acid

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Butiratos / Neoplasias Colorrectales / Proteína p53 Supresora de Tumor / Proteína de Susceptibilidad a Apoptosis Celular Límite: Animals / Humans Idioma: En Revista: Int J Oncol Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article Pais de publicación: Grecia

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