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Prognostic factors for COVID-19 patients.
Önal, Ugur; Aydin Güçlü, Özge; Akalin, Halis; Aylin Acet Öztürk, Nilüfer; Semet, Cihan; Demirdögen, Ezgi; Görek Dilektasli, Asli; Saglik, Imran; Kazak, Esra; Özkaya, Güven; Coskun, Funda; Ediger, Dane; Heper, Yasemin; Ursavas, Ahmet; Yilmaz, Emel; Uzaslan, Esra; Karadag, Mehmet.
Afiliación
  • Önal U; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Uludag University, Bursa, Turkey. uguronal@uludag.edu.tr.
  • Aydin Güçlü Ö; Department of Pulmonary Diseases, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Akalin H; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Aylin Acet Öztürk N; Department of Pulmonary Diseases, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Semet C; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Demirdögen E; Department of Pulmonary Diseases, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Görek Dilektasli A; Department of Pulmonary Diseases, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Saglik I; Department of Microbiology, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Kazak E; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Özkaya G; Department of Biostatistics, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Coskun F; Department of Pulmonary Diseases, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Ediger D; Department of Pulmonary Diseases, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Heper Y; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Ursavas A; Department of Pulmonary Diseases, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Yilmaz E; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Uzaslan E; Department of Pulmonary Diseases, Faculty of Medicine, Uludag University, Bursa, Turkey.
  • Karadag M; Department of Pulmonary Diseases, Faculty of Medicine, Uludag University, Bursa, Turkey.
J Infect Dev Ctries ; 16(3): 409-417, 2022 03 31.
Article en En | MEDLINE | ID: mdl-35404844
INTRODUCTION: Determining prognostic factors in patients with coronavirus disease (COVID-19) can have great impact on treatment planning and follow-up strategies. Herein, we aimed to evaluate prognostic factors and clinical scores for confirmed COVID-19 patients in a tertiary-care hospital in the Bursa region of Turkey. METHODOLOGY: Patients who had been diagnosed with COVID-19 microbiologically and/or radiologically between March and October 2020 in a tertiary-care university hospital were enrolled retrospectively. Adult patients (≥ 18 years) with a clinical spectrum of moderate, severe, or critical illness were included. The dependent variable was 30-day mortality and logistic regression analysis was used to evaluate any variables with a significant p value (< 0.05) in univariate analysis. RESULTS: A total of 257 patients were included in the study. The mortality rate (30-day) was 14.4%. In logistic regression analysis, higher scores on sequential organ failure assessment (SOFA) (p < 0.001, odds ratio (OR) = 1.86, 95% CI = 1.42-2.45) and CURB-65 pneumonia severity criteria (p = 0.001, OR = 2.60, 95% CI = 1.47-4.57) were found to be significant in predicting mortality at admission. In deceased patients, there were also significant differences between the baseline, day-3, day-7, and day-14 results of D-dimer (p = 0.01), ferritin (p = 0.042), leukocyte (p = 0.019), and neutrophil (p = 0.007) counts. CONCLUSIONS: In our study of COVID-19 patients, we found that high SOFA and CURB-65 scores on admission were associated with increased mortality. In addition, D-dimer, ferritin, leukocyte and neutrophil counts significantly increased after admission in patients who died.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Humans Idioma: En Revista: J Infect Dev Ctries Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2022 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Humans Idioma: En Revista: J Infect Dev Ctries Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2022 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Italia