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Screening of σ2 Receptor Ligands and In Vivo Evaluation of 11C-Labeled 6,7-Dimethoxy-2-[4-(4-methoxyphenyl)butan-2-yl]-1,2,3,4-tetrahydroisoquinoline for Potential Use as a σ2 Receptor Brain PET Tracer.
Kim, Ho Young; Lee, Ji Youn; Hsieh, Chia-Ju; Riad, Aladdin; Izzo, Nicholas J; Catalano, Susan M; Graham, Thomas J A; Mach, Robert H.
Afiliación
  • Kim HY; Department of Radiology, University of Pennsylvania, Vagelos Laboratories, 1012, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Lee JY; Department of Radiology, University of Pennsylvania, Vagelos Laboratories, 1012, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Hsieh CJ; Department of Radiology, University of Pennsylvania, Vagelos Laboratories, 1012, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Riad A; Department of Radiology, University of Pennsylvania, Vagelos Laboratories, 1012, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Izzo NJ; Cognition Therapeutics Inc., Pittsburgh, Pennsylvania 15203-5118, United States.
  • Catalano SM; Cognition Therapeutics Inc., Pittsburgh, Pennsylvania 15203-5118, United States.
  • Graham TJA; Department of Radiology, University of Pennsylvania, Vagelos Laboratories, 1012, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Mach RH; Department of Radiology, University of Pennsylvania, Vagelos Laboratories, 1012, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
J Med Chem ; 65(8): 6261-6272, 2022 04 28.
Article en En | MEDLINE | ID: mdl-35404616
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores sigma / Tetrahidroisoquinolinas Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores sigma / Tetrahidroisoquinolinas Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos