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Primary herpes simplex virus type 1 infection with acute liver failure in solid organ transplantation: Report of three cases and review.
Arana, Carolt; Cofan, Frederic; Ruiz, Pablo; Hermida, Evelyn; Fernández, Javier; Colmenero, Jordi; Forns, Xavier; Escude, Laia; Cucchiari, David; Moreno, Asunción; Bodro, Marta; Herrera, Sabina; Rodriguez, Camino; Paredes, David; Diekmann, Fritz.
Afiliación
  • Arana C; Nephrology Service, Hospital Clínic-IDIBAPS, Barcelona, Spain.
  • Cofan F; Nephrology Service, Hospital Clínic-IDIBAPS, Barcelona, Spain.
  • Ruiz P; Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Spain.
  • Hermida E; Nephrology Service, Hospital Clínic-IDIBAPS, Barcelona, Spain.
  • Fernández J; Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Spain.
  • Colmenero J; Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Spain.
  • Forns X; Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Spain.
  • Escude L; Liver Unit, Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Spain.
  • Cucchiari D; Nephrology Service, Hospital Clínic-IDIBAPS, Barcelona, Spain.
  • Moreno A; Infectious Diseases Service, Hospital Clínic, IDIBAPS, Barcelona, Spain.
  • Bodro M; Infectious Diseases Service, Hospital Clínic, IDIBAPS, Barcelona, Spain.
  • Herrera S; Infectious Diseases Service, Hospital Clínic, IDIBAPS, Barcelona, Spain.
  • Rodriguez C; Transplant Coordination Service, Hospital Clínic, Barcelona, Spain.
  • Paredes D; Transplant Coordination Service, Hospital Clínic, Barcelona, Spain.
  • Diekmann F; Nephrology Service, Hospital Clínic-IDIBAPS, Barcelona, Spain.
IDCases ; 28: e01485, 2022.
Article en En | MEDLINE | ID: mdl-35392601
Herpes virus infections is not uncommon in solid organ transplantation patients. We report 3 cases with primary Herpes simplex virus type-1 (HSV1) infection with acute liver failure (ALF). This is a rare and potentially fatal entity that could be a donor-derived infection. Although the initial clinical presentation is non-specific, it should be considered as a differential diagnosis in HSV-negative serology patients with liver failure and empirical treatment must be started in combination with a drastic reduction of immunosuppression. A strategy of HSV prophylaxis for pre-transplant HSV seronegative patients must be stablished in order to reduce the risk of clinical disease.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: IDCases Año: 2022 Tipo del documento: Article País de afiliación: España Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: IDCases Año: 2022 Tipo del documento: Article País de afiliación: España Pais de publicación: Países Bajos