Brain-targeting, acid-responsive antioxidant nanoparticles for stroke treatment and drug delivery.

Zhang, Shenqi; Peng, Bin; Chen, Zeming; Yu, Jiang; Deng, Gang; Bao, Youmei; Ma, Chao; Du, Fengyi; Sheu, Wendy C; Kimberly, W Taylor; Simard, J Marc; Coman, Daniel; Chen, Qianxue; Hyder, Fahmeed; Zhou, Jiangbing; Sheth, Kevin N

Zhang, Shenqi; Peng, Bin; Chen, Zeming; Yu, Jiang; Deng, Gang; Bao, Youmei; Ma, Chao; Du, Fengyi; Sheu, Wendy C; Kimberly, W Taylor; Simard, J Marc; Coman, Daniel; Chen, Qianxue; Hyder, Fahmeed; Zhou, Jiangbing; Sheth, Kevin N.

Afiliación

Zhang S; Department of Neurosurgery, USA.
Peng B; Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China.
Chen Z; Department of Neurosurgery, USA.
Yu J; Department of Neurosurgery, USA.
Deng G; Department of Neurosurgery, USA.
Bao Y; Department of Neurosurgery, USA.
Ma C; Department of Neurosurgery, USA.
Du F; Department of Neurosurgery, USA.
Sheu WC; Department of Neurosurgery, USA.
Kimberly WT; Department of Biomedical Engineering, USA.
Simard JM; Department of Neurology, Division of Neurocritical Care, Massachusetts General Hospital, Boston, MA, USA.
Coman D; Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Chen Q; Department of Radiology and Biomedical Imaging, USA.
Hyder F; Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China.
Zhou J; Department of Biomedical Engineering, USA.
Sheth KN; Department of Radiology and Biomedical Imaging, USA.

Bioact Mater ; 16: 57-65, 2022 Oct.

Article en En | MEDLINE | ID: mdl-35386312

Palabras clave

A-BAM NPs, A-BAM NPs; ALT, alanine aminotransferase; AST, aspartate aminotransferase; Acid-triggered release; Antioxidant nanoparticles; BA, betulinic acid; BAM, betulinic amine; BBB, blood brain barrier; BIRDS, biosensor imaging of redundant deviation in shifts; BT, ß-sitosterol; DLS, dynamic light scattering; DTA, dehydrotrametenolic acid; DYDA, diketohydrindylidene diketohydrindamine; Drug delivery; GA, glycyrrhetic acid; Ischemic stroke; LCMS, liquid chromatography mass spectrometry; LP, lupeol; MCAO, middle cerebral artery occlusion; NA1; NMR, nuclear magnetic resonance; NP, nanoparticle; OA, oleanolic acid; PAA, poricoic acid; PEG, polyethylene glycol; SA, sumaresinolic acid; SEM, scanning electron microscopy; ST, stigmasterol; TEM, transmission electron microscope; TTC, triphenyltetrazolium chloride; UA, ursolic acid; tPA, tissue-type plasminogen activator

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Bioact Mater Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: China

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