Your browser doesn't support javascript.
loading
Use of Investigator 24plex GO! To analyse allele frequencies of 21 autosomal STRs in the population of Veracruz state, Mexico.
Melo, Guadalupe; Uscanga, Keren; López-Armenta, Mauro; Avilés-Villada, David; Hernández-Romano, Pablo; Rangel-Villalobos, Héctor; Aquino, P; Meza, A; Jiménez, Carlos; Denis, Patricia; López-Balderas, Nayali.
Afiliación
  • Melo G; UV-GC-212 "Ciencias Forenses" Instituto de Medicina Forense, Universidad Veracruzana, Boca del Río, México.
  • Uscanga K; Maestría en Medicina Forense, Instituto de Medicina Forense, Universidad Veracruzana, Boca del Río, México.
  • López-Armenta M; Laboratorio de Genética, Instituto de Servicios Periciales y Ciencias Forenses del Poder Judicial de la CDMX, Ciudad de México, Mexico.
  • Avilés-Villada D; Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.
  • Hernández-Romano P; Centro Estatal de la Transfusión Sanguínea del Estado de Veracruz, Veracruz, México.
  • Rangel-Villalobos H; Laboratorio de Genética, Hospital de Alta Especialidad de Veracruz, Veracruz, México.
  • Aquino P; Instituto de Investigación en Genética Molecular, Centro Universitario de la Ciénega, Universidad de Guadalajara (CUCiénega-UdeG), Ocotlán, México.
  • Meza A; Facultad de Medicina, Universidad Veracruzana, Veracruz, México.
  • Jiménez C; Facultad de Medicina, Universidad Veracruzana, Veracruz, México.
  • Denis P; UV-GC-212 "Ciencias Forenses" Instituto de Medicina Forense, Universidad Veracruzana, Boca del Río, México.
  • López-Balderas N; UV-GC-212 "Ciencias Forenses" Instituto de Medicina Forense, Universidad Veracruzana, Boca del Río, México.
Ann Hum Biol ; 49(2): 164-169, 2022 Mar.
Article en En | MEDLINE | ID: mdl-35380906
BACKGROUND: Mexican population databases for autosomal STRs are scarce, and no previous studies have been performed with the Qiagen Investigator 24plex GO! AIM: To analyse the frequency of 21 autosomal short tandem repeat (STR) loci and forensic parameters in individuals from Veracruz state, Mexico. SUBJECTS AND METHODS: A total of 234 unrelated individuals were analysed with the Investigator 24plex GO! Kit, which includes the following autosomal STRs: TH01, D3S1358, vWA, D21S11, TPOX, D1S1656, D12S391, SE33, D10S1248, D22S1045, D19S433, D8S133879, D2S1338, D2S441, D18S51, FGA, D16S539, CSF1PO, D13S317, D5S818, and D7S820. Allele frequencies, forensic parameters, and relationships with neighbouring Mexican populations were estimated. RESULTS: The STRs analysed were in Hardy-Weinberg Equilibrium (HWE). The combined matching probability and combined PE were 1.5266 E-24 and 0.999999988711, respectively. The D18S51 and SE33 loci presented the highest Ho (0.8974 and 0.8932) and PE (0.7902 and 0.7815), respectively. The highest PIC (0.9337) and PD (0.9894) values corresponded to SE33. Conversely, D22S1045 had the lowest PIC and PE (0.5533 and 0.3546, respectively). A population cluster among southern Mexican populations, which included non-differentiation between Guerrero and Veracruz states was detected. CONCLUSION: The forensic efficacy of the 21 STRs analysed by the Investigator 24plex GO! Kit was evaluated in the Veracruz state. Moreover, new population clusters that have not yet been described and are related to geographic regions were identified, and these are in agreement with previously reported ancestral differences.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Repeticiones de Microsatélite / Genética de Población Límite: Humans País/Región como asunto: Mexico Idioma: En Revista: Ann Hum Biol Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Repeticiones de Microsatélite / Genética de Población Límite: Humans País/Región como asunto: Mexico Idioma: En Revista: Ann Hum Biol Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido