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Per- and polyfluoroalkyl substances (PFASs) in the blood of police and Beagle dogs from Harbin, China: Concentrations and associations with hematological parameters.
You, Dan; Chang, Xiaochen; Guo, Lijun; Xie, Wei; Huang, Shuping; Li, Xiang; Chai, Hongliang; Wang, Yajun.
Afiliación
  • You D; College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, PR China. Electronic address: dlslyd41@nefu.edu.cn.
  • Chang X; School of Environmental Science and Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China. Electronic address: changxiaochen@ioz.ac.cn.
  • Guo L; College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, PR China. Electronic address: 1120883655@qq.com.
  • Xie W; College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, PR China. Electronic address: Sherlvy2020@163.com.
  • Huang S; College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, PR China. Electronic address: sph1971855748@163.com.
  • Li X; College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, PR China. Electronic address: xiang_li1120@hotmail.com.
  • Chai H; College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, PR China. Electronic address: Hongliang_Chai@hotmail.com.
  • Wang Y; College of Wildlife and Protected Area, Northeast Forestry University, Harbin, 150040, PR China. Electronic address: wangyajun@nefu.edu.cn.
Chemosphere ; 299: 134367, 2022 Jul.
Article en En | MEDLINE | ID: mdl-35358559
Per-and polyfluoroalkyl substances (PFASs) have been omnipresent in the environment and marine organisms. However, little is known about these compounds and their associations with hematological parameters in dogs. In this research, we investigated the concentrations and distributions of PFASs in the blood of dogs and explored the associations between PFASs concentrations in blood and hematological parameters. Perfluorooctanoate (PFOA) was found to be the dominant PFAS in the blood (54.23%), followed by perfluorobutyric acid (PFBA) (16.05%) and perfluorooctanesulfonate (PFOS) (12.05%). On average, PFASs concentration in dogs was 3.553 ng/mL (SD: 2.146). Moreover, age is a key factor influencing the levels of PFBA, PFOA, and PFBS in males, as well as seven PFASs (6:2 Cl-PFESA, PFBA, PFOA, PFOS, PFHxS, PFDA, and PFNA) in female dogs' blood. The results revealed that PFHxS in dietary food accounted for most of the total daily PFASs consumption. We also discovered that greater PFASs exposure (including PFOA and PFOS) could significantly increase amylase (AMY) and decrease cholesterol (CHOL) levels. Furthermore, there are linear relationships between PFDA, PFNA and many biochemical parameters (AMY, CHOL, albumin/globulin (A/G), blood urea nitrogen (BUN), alkaline phosphatase (ALP), creatinine (CREA)). Thus, PFAS accumulation has a certain influence on dogs' health, and we must pay attention to the potential threat posed by these elements to dogs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Alcanesulfónicos / Contaminantes Ambientales / Fluorocarburos Tipo de estudio: Risk_factors_studies Límite: Animals / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Chemosphere Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Alcanesulfónicos / Contaminantes Ambientales / Fluorocarburos Tipo de estudio: Risk_factors_studies Límite: Animals / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Chemosphere Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido