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Synchronous visceral Kaposi sarcoma and extracavitary primary effusion lymphoma in a patient with AIDS.
Bradshaw, Stanley; Oertling, Estelle; Rezigh, Austin.
Afiliación
  • Bradshaw S; University of Texas Southwestern Medical Center, Dallas, Texas, USA.
  • Oertling E; University of Texas Southwestern Medical Center, Dallas, Texas, USA.
  • Rezigh A; University of Texas Southwestern Medical Center, Dallas, Texas, USA austin.rezigh@utsouthwestern.edu.
BMJ Case Rep ; 15(3)2022 Mar 29.
Article en En | MEDLINE | ID: mdl-35351773
While infection should always lead the differential when a patient with AIDS presents with fever, inflammatory and malignant aetiologies should also be considered. With profound immunocompromise, malignancies can develop as sequelae of viral oncogene expression. Human herpesvirus 8 (HHV-8) infection drives several AIDS-related cancers including Kaposi sarcoma (KS), multicentric Castleman disease and primary effusion lymphoma (PEL), which can present simultaneously with variable clinical features. Herein, we describe a case of synchronous visceral KS and extracavitary PEL in a patient with AIDS. The patient was treated with systemic chemotherapy and remains in remission after four cycles. We review other cases of copresenting HHV-8-related malignancies, explore the salient pathomechanisms and clinical features of these cancers and discuss treatment strategies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcoma de Kaposi / Síndrome de Inmunodeficiencia Adquirida / Enfermedad de Castleman / Herpesvirus Humano 8 / Linfoma de Efusión Primaria Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: BMJ Case Rep Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcoma de Kaposi / Síndrome de Inmunodeficiencia Adquirida / Enfermedad de Castleman / Herpesvirus Humano 8 / Linfoma de Efusión Primaria Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: BMJ Case Rep Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido