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Pharmacotherapy focusing on for the management of otitis media with effusion in children: Systematic review and meta-analysis.
Ikeda, Ryoukichi; Hidaka, Hiroshi; Ito, Makoto; Kamide, Yosuke; Kuroki, Haruo; Nakano, Atsuko; Yoshida, Haruo; Takahashi, Haruo; Iino, Yukiko; Harabuchi, Yasuaki; Kobayashi, Hitome.
Afiliación
  • Ikeda R; Department of Otorhinolaryngology-Head and Neck Surgery, Tohoku University School of Medicine. Electronic address: ryoukich@hotmail.com.
  • Hidaka H; Department of Otorhinolaryngology, Head and Neck Surgery, Kansai Medcal University.
  • Ito M; Department of Pediatric Otolaryngology, Jichi Children's Medical Center Tochigi, Jichi Medical University.
  • Kamide Y; Kamide Ear Nose and Throat Clinic.
  • Kuroki H; Sotobo Children's Clinic.
  • Nakano A; Division of Otorhinolaryngology, Chiba Children's Hospital.
  • Yoshida H; Department of Otolaryngology, Nagasaki Harbor Medical Center.
  • Takahashi H; Department of Otolaryngology, Nagasaki Harbor Medical Center.
  • Iino Y; Department of Otolaryngology, Tokyo-Kita Medical Center.
  • Harabuchi Y; Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University.
  • Kobayashi H; Department of Otorhinolaryngology, Showa University School of Medicine.
Auris Nasus Larynx ; 49(5): 748-754, 2022 Oct.
Article en En | MEDLINE | ID: mdl-35341623
OBJECTIVE: To examine the evidence for treating children with otitis media with effusion with pharmacotherapy. DATA SOURCES: For the systematic review, data were retrieved from PubMed, Cochrane database, and the Japan Medical Abstracts Society Database (1st January 1995 through 31th May 2019). STUDY SELECTION: Articles addressing pharmacotherapy for the management of otitis media with effusion in children were selected in English. DATA EXTRACTION: The database was searched using the keywords "Otitis Media with effusion or secretory otitis media" and the following medical agents: carbocysteine, antihistamines, leukotriene receptor antagonist, and steroid nasal spray. DATA SYNTHESIS: After a critical review of 18 studies, studies addressing steroid nasal spray were eligible for quantitative synthesis. Intranasal steroids for OME showed no benefit with OR 1.155 (95% CI 0.834-1.598) within one month. Conversely, intranasal steroids have effects for OME with OR 1.858 (95% CI 1.240-2.786) for more than one month. CONCLUSIONS: We found evidence of benefit from treatment of OME in children with intranasal steroids and S-carboxymethylcysteine at longer-term follow-up.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Otitis Media / Otitis Media con Derrame Tipo de estudio: Systematic_reviews Límite: Child / Humans Idioma: En Revista: Auris Nasus Larynx Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Otitis Media / Otitis Media con Derrame Tipo de estudio: Systematic_reviews Límite: Child / Humans Idioma: En Revista: Auris Nasus Larynx Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos