Your browser doesn't support javascript.
loading
Intravascular Gas Exchange: Physiology, Literature Review, and Current Efforts.
Straube, Tobias L; Farling, Stewart; Deshusses, Marc A; Klitzman, Bruce; Cheifetz, Ira M; Vesel, Travis P.
Afiliación
  • Straube TL; Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina. tobias.straube@duke.edu.
  • Farling S; Department of Civil and Environmental Engineering, Duke University, Durham, North Carolina.
  • Deshusses MA; Department of Civil and Environmental Engineering, Duke University, Durham, North Carolina; and Duke Global Health Institute, Duke University, Durham, North Carolina.
  • Klitzman B; Kenan Plastic Surgery Research Labs, Duke University School of Medicine, Durham, North Carolina; and Department of Biomedical Engineering, Duke University, Durham, North Carolina.
  • Cheifetz IM; Department of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, Ohio.
  • Vesel TP; Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Respir Care ; 67(4): 480-493, 2022 04.
Article en En | MEDLINE | ID: mdl-35338096
Acute respiratory failure with inadequate oxygenation and/or ventilation is a common reason for ICU admission in children and adults. Despite the morbidity and mortality associated with acute respiratory failure, few proven treatment options exist beyond invasive ventilation. Attempts to develop intravascular respiratory assist catheters capable of providing clinically important gas exchange have had limited success. Only one device, the IVOX catheter, was tested in human clinical trials before development was halted without FDA approval. Overcoming the technical challenges associated with providing safe and effective gas exchange within the confines of the intravascular space remains a daunting task for physicians and engineers. It requires a detailed understanding of the fundamentals of gas transport and respiratory physiology to optimize the design for a successful device. This article reviews the potential benefits of such respiratory assist catheters, considerations for device design, previous attempts at intravascular gas exchange, and the motivation for continued development efforts.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Dificultad Respiratoria / Insuficiencia Respiratoria Límite: Adult / Child / Humans Idioma: En Revista: Respir Care Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Dificultad Respiratoria / Insuficiencia Respiratoria Límite: Adult / Child / Humans Idioma: En Revista: Respir Care Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos